Geometric target weights reduced blocked selective 50% output cuts from 261 to 101 of 486 connections in one adult worm model at baseline release probability 0.5

We asked how shared chemical synapse sites limit a selective output change. We used eight C. elegans brain maps and a direct output model. Each site has one release probability, shared across its listed targets. We minimized one target output while all other target outputs stayed at baseline. Separate site increases could compensate for decreases. With unit effects and baseline probability 0.5, a 50% selective cut was not possible for 212 of 443 and 261 of 486 connections with at least five sites in the two adult maps. The mean maximum cuts were 49.8% and 48.5%. An added check used the source study's positive geometric target weights in the second adult map. On the same 486 connections, the blocked count fell from 261 to 101 and the mean maximum cut rose to 69.7%. These weights are model estimates, not measured transmission strengths. Another added check allowed 10% changes in each other output. It left 149 of 443 and 167 of 486 connections below a 50% selective cut in the unit effect models. We give a linear optimization tool, exact model statements, source provenance, compact inputs, figures and numerical optimality certificates. Shared site structure constrains selective direct output in these models, but counts alone do not fix the limit. The study does not measure plasticity or establish one release parameter per anatomical site. Site effect weights, baseline probabilities and target preservation are material assumptions.

C. elegans · connectome · polyadic synapse · presynaptic release · selective output · linear programming · plasticity model