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q-bio.NC · Neurons and Cognition

Two Mahalanobis distance limits raised mean known-site rejection more than mean unknown-shaft rejection for 20–100 ms voltage in five offline SEEG sessions at matched nominal 80% acceptance

This study tested whether a lower distance limit can help a SEEG response check reject stimulation shafts absent from training. It used public OpenNeuro ds004457 version 1.0.2, with five sessions, 183 stimulation sites, and 732 distinct test pulses. One entire shaft was excluded from training in each of 38 tests. The two rules accepted the same number of early known-site calibration pulses. The main test used 20–100 ms voltage and nominal 80% calibration acceptance. Two Mahalanobis distance limits raised mean unknown-shaft rejection from 32.70% to 35.72%. Mean known-site rejection rose from 18.88% to 22.12%. The difference between these rates fell by 0.21 percentage points. Its descriptive patient bootstrap interval was −2.81 to +3.06 points. This does not establish equivalence. A secondary relative-distance score lost separation in all five people. The package provides raw-file retrieval with hashes, voltage bins, code, models, pulse scores, three figures, and reproduction checks. A fresh raw extraction reproduced all ten input files byte for byte. These are reused offline sessions with interleaved calibration and tests. The result does not show live interface safety or benefit.

SEEG · Mahalanobis distance · withheld-shaft rejection · intracranial stimulation · calibration acceptance · offline evaluation

Admitted 1 citing publication

References

7
  1. usesA fixed covariance rule gave higher SEEG site accuracy than a diagonal rule in offline tests from five patient sessions sci:sha256:1407cd9ac712a4bcd551a3738cc90c3fab309b871572cbd6fc644b41555f7886

    The study uses the fixed covariance rule with a 0.5 diagonal weight. It does not select a new weight from test results.

  2. A relative distance score gave higher mean AUROC but accepted most SEEG responses from withheld shafts in five offline sessions sci:sha256:e20e4bb067514e9b579810b8a02215225203afff58108a2c2ada8ec7689b98d1

    [Legacy relation: reproduces] The new run reproduced all 304 saved 95% upper-limit result rows within saved text precision. The package preserves the unchanged reference table and the numerical check. This citation concerns that numerical result.

  3. usesA relative distance score gave higher mean AUROC but accepted most SEEG responses from withheld shafts in five offline sessions sci:sha256:e20e4bb067514e9b579810b8a02215225203afff58108a2c2ada8ec7689b98d1

    This study uses the saved voltage bins, event tables, contacts, model code, and relative-distance score from this publication. It adds a lower limit at a fixed calibration rejection count.

  4. usesA fixed SEEG distance rule accepted most pulses from unlearned stimulation shafts in five sessions sci:sha256:ecfcd951080fd4edc42a41327003efe86593c463b7a6afdbbcad8732b89e3028

    The study uses the test that excludes one entire stimulation shaft and preserves its early fit, early calibration, and late test roles.

  5. usesRemoving missing features raised mean site accuracy for 20 to 100 ms responses under known simulated contact loss in five SEEG sessions sci:sha256:ee49903b43a054e26fbb0d85370a8cc3bbeb395ca7baf6c0069fcd7329eac507

    The study uses the fixed contact configuration, extraction code, and 5 ms voltage bins. A fresh download and extraction reproduced all ten input files byte for byte.

  6. usesdoi:10.18112/openneuro.ds004457.v1.0.2

    The analysis used the OpenNeuro ds004457 version 1.0.2 source files; the pinned source manifest and retrieval verification identify the snapshot.

  7. doi:10.1523/JNEUROSCI.1325-22.2023

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