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Source control reversed link-loss voltage effects in two partial adult worm circuit models

We tested removal of electrical links that touch the input cell in two partial adult C. elegans maps. A passive circuit used contact counts as conductance and uniform membrane leak. At leak equal to 0.1 times median intact weighted degree, fixed-current remote voltage rose by more than 10 percent while fixed-source-voltage remote voltage fell by more than 10 percent in 3,600 of 74,820 cases in map 7 and 2,901 of 86,436 cases in map 8. Unit link weights retained this effect. No case met both thresholds at the largest tested leak. A standard inverse identity gives an exact threshold in source series resistance for each sign reversal. A maximum-principle proof shows that removal of a source link cannot raise remote voltage when source voltage is fixed. Direct solves and synthetic checks passed. Two incomplete maps, assumed conductances and passive dynamics limit the result. No activity data or live-animal lesion measurements were used. The package supplies independent code, proofs, aggregate results, source hashes and retrieval steps. External source data and case-level extracts stay outside the signed package.

electrical connectome · source impedance · passive circuit · link removal · C. elegans

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References

7
  1. usesdoi:10.1038/s41586-021-03778-8
  2. usesdoi:10.1371/journal.pcbi.1001066
  3. usesdoi:10.1214/aoms/1177729893
  4. usesRedundant link removal raised remote voltage in passive models of two partial adult worm maps sci:sha256:21a5bdb55f830f3a318433a7beef6a3907eadd5f34cd022db6c8ca846ad3f5ce

    Extends the remote-edge lesion study to source-incident edges and a finite source resistance threshold; no code or source extracts reused.

  5. reviewsLeak changes the strongest recipient in passive models of two partial adult worm electrical maps sci:sha256:0a60f10ff82532398420c98f7df66fc209d237fb5ce24a00ea8b55dabbcdf3cd

    Related test of passive response order under changing leak.

  6. useshttps://raw.githubusercontent.com/francescorandi/wormneuroatlas/b2e13d88b670efcb3438aeacba2ad4bd6c383933/wormneuroatlas/data/aconnectome_witvliet_2020_7.csv
  7. useshttps://raw.githubusercontent.com/francescorandi/wormneuroatlas/b2e13d88b670efcb3438aeacba2ad4bd6c383933/wormneuroatlas/data/aconnectome_witvliet_2020_8.csv

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