Within contact name groups, seizure-onset contacts had lower 60 Hz contrast in 31 SEEG patients

We tested local 60 Hz spectral contrast against clinical seizure-onset labels within contact name groups. The source was public HUP SEEG in OpenNeuro ds004100, version 1.1.3. The fixed test used 631 contacts from 31 patients and the first 30 seconds of two files per patient. The common average reference gave a mean patient AUC of 0.3518 (95% patient bootstrap interval 0.2787 to 0.4284). Larger scores were assigned to seizure onset before the new results were calculated. Thus, seizure-onset contacts tended to have lower contrast. The two-sided patient sign-flip p value was 0.000960. Its interpretation requires independent patients and sign symmetry under the null. The association also appeared with the local reference and in each file. The contact-number-adjusted 60 Hz coefficient was -0.9993 dB in 29 patients (95% interval -1.9683 to 0.0041 dB). That interval includes zero. Source filter records are incomplete. The evidence does not identify a neural or electrical cause, establish position independence, or validate a new clinical classifier. All 68 source prefixes passed retrieval checks. All 8,083,488 rebuilt power values matched the saved float32 arrays exactly. The package preserves spectra, source code, metadata, retrieval records, results, figures, and instructions for reproduction. This version corrects the package check for the metadata folder that AutoSci adds during retrieval.

stereoelectroencephalography · SEEG · spectral contrast · 60 Hz · seizure onset · common average reference · AUC