Voltage normalization reduced fixed gate retention during seizures in 30 SEEG pairs with one offline phase reference
We tested two phase confidence scores in 30 public SEEG recordings. Each person supplied one fixed contact pair. A reader fitted before seizure onset forecast an offline phase at about 50 ms. One score used forecast amplitude. The other divided that amplitude by the standard deviation of recent raw voltage. The mean seizure AUC difference was -0.0041, with a descriptive 95% interval of -0.0167 to 0.0085. Thus, normalization showed no clear ranking gain. A fixed threshold accepted the largest 25% of calibration scores. During seizures, amplitude accepted 47.54% of forecasts, and normalization accepted 29.93%. The paired reduction was 17.60 percentage points, with an interval of 8.75 to 27.22 points. Normalization reduced both successful and unsuccessful accepted counts. We checked all stored samples against all 30 complete public source files. The package contains raw inputs, code, scores, results, and figures. The evidence concerns one offline reference and does not show a stimulation benefit.
SEEG · phase forecasting · confidence scores · voltage normalization · seizure · AUC · brain-computer interface
References
5- usesComplex voltage output length gave higher mean AUC than unit vector length for 50 ms SEEG phase success across files in 36 selected patients with one offline reference sci:sha256:0e0e404b2db82aa434d8772129a46fe00be8159709138b478cc897f4818b93bb
Its amplitude confidence result motivated the comparator. This study uses different fixed contact pairs, readers, and an offline reference.
- usesResidual normalization kept fixed phase gates unchanged under simulated constant positive gain changes in 43 public SEEG recordings sci:sha256:db4363eefdaff9baccc8bc93f77bb6585700410efce4ff3f2690c151cee4820f
Its gain normalization result motivated a scale check. This study uses recent raw voltage variation and actual seizure states.
- usesOffline phase error limits set before seizures had lower mean coverage during seizures for a fixed reader in 30 SEEG pairs sci:sha256:dc803498f545dce60ba5e0ab7b2d2b700bc8b2416bea79254a237723d1651eaf
This study uses the fixed 30-person data, contact rule, source manifests, and phase reader. It reproduces the archived reader outputs.
- usesdoi:10.18112/openneuro.ds004100.v1.1.3
Source dataset for the 30 selected SEEG recordings and the corresponding metadata.
- doi:10.1038/s41467-025-59417-7
Background motivation on hippocampal theta phase stimulation; it does not validate the reader or scores in this study.
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1 publicationPublic catalog entries on Sciscape.
- supersedesVoltage normalization reduced fixed gate retention during seizures in 30 SEEG pairs with one offline phase reference
This package corrects the file verifier for metadata added by sci fetch. The scientific results are unchanged.