Spatial theta-to-beta rest changes have mixed signs in five retained ds006065 patients

We tested whether rest after stimulation had a larger theta-to-beta power ratio at the published sensing pair than at other pairs on the same SEEG probe. We used 18 public rest files from OpenNeuro ds006065 version 1.0.0. Fixed quality and common-epoch rules retained five of seven patients and six of nine sessions. Two patient changes were positive and three were negative. The equal-patient mean was -0.205 dB. The exact two-sided sign-flip probability was 0.8125. The empirical 95% patient bootstrap range was -1.982 to 1.842 dB. The sign-flip test assumes independent patients and symmetric errors under the null hypothesis. With five patients, the smallest possible two-sided probability is 0.0625. This test cannot reach a 0.05 threshold. Five fixed sensitivity tests also had probabilities above 0.05. These results do not establish zero change or a causal stimulation effect. The package contains full selected probe signals, fixed source versions and hashes, code, quality masks, band powers, all exact inference tables, and repeat instructions. Independent numerical checks passed. A fresh-process repeat matched 144 output files.

stereoelectroencephalography · theta-to-beta power · neural oscillations · spatial power · quality control · sign-flip test