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Bootstrap width ranked large peak shifts in five-patient SEEG data (mean AUC 0.667)

We tested whether a bootstrap range from the first five pulses could flag a large peak shift in the next five pulses. We used public OpenNeuro ds004457 v1.0.2 data from five SEEG patients. We selected the top 20 percent of pairs by training energy. Each peak was the largest absolute voltage from 50 to 250 ms. Range width gave mean patient AUC 0.667 for shifts above 20 ms. All five AUC values exceeded 0.5. The exact two-sided patient test gave p = 0.0625. The training range contained 166 of 218 later peaks. One of 16 narrow ranges had a large later shift. A post-plan line-frequency projection gave mean AUC 0.655. This sample does not establish a population effect or a 95 percent future range. The package has source windows, exact bootstrap code, results, source hashes, and a verified raw rebuild.

stereoelectroencephalography · SEEG · electrical stimulation · peak timing · bootstrap · uncertainty · area under the curve · repeatability

Admitted 2 citing publications

References

5
  1. usesStrong SEEG responses had 48 percent mean agreement within 10 ms for 20–300 ms peaks from unused pulse groups in five patients sci:sha256:092a51ee3f6e31e7e25efe91f7903b2e4d48401f0bb5278e7941385636c1c021

    Its peak repeat results from the same five patients informed the question before the local plan. It is prior context from the same sample.

  2. usesA variance rule reduced average 50 to 250 ms SEEG prediction error in five patients with separate five pulse groups sci:sha256:335cdede136528c2246142ff023095aeaebe4b09b0b78a45abc1cd9dc2cc0387

    We used its pulse windows, source metadata, source locks, and extraction tools. A fresh raw rebuild matched all saved arrays.

  3. usesdoi:10.18112/openneuro.ds004457.v1.0.2

    Source SEEG data, version 1.0.2; the publication used this recorded release.

  4. doi:10.1523/JNEUROSCI.1325-22.2023

    Source study for the shared SEEG recordings and scientific context.

  5. doi:10.1371/journal.pcbi.1011105

    Related work on measuring response shape and duration cited as motivation.

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