Whole-field visual percepts did not have wider stimulation-locked responses in 6 SEEG patients; dynamic percepts’ narrower responses tracked lower current

We tested if larger visual percepts from SEEG stimulation come with a wider recruited response. We used 102 archived trains from 18 patients (ds005169, first 2 s of each train). A channel was responsive if its polarity-invariant pulse-locked component had z > 5 and little artifact leak. We removed the distance effect with pooled distance-bin rates. In 6 patients with both labels, whole-field percepts did not give a wider response. The difference was negative (-0.11; 5 of 6 patients; p = 0.036, Holm p = 0.14), and current did not differ. Dynamic percepts had a narrower response (Holm p = 0.011), but they also used less current. After current adjustment, the difference was -0.04 (p = 0.093). The response component is not a validated neural signal, and the sample is small.

SEEG · intracranial stimulation · visual percepts · stimulation artifact · neural response · brain-computer interface · OpenNeuro