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A prior voltage model did not reduce mean forecast error for 20–500 ms pulse size at later sites in eight SEEG sessions

A prior voltage model did not reduce mean forecast error for pulse size at later stimulation sites in eight SEEG sessions. We used public OpenNeuro ds004696, version 1.0.1. The target was log voltage size at 20–500 ms after a pulse. The input was log voltage size at -980 to -500 ms. First-five pulses at earlier sites fitted one slope per patient. First-five pulses at each later site fitted local means. Final-five pulses at later sites tested the forecasts. The constant comparison used the same local calibration. The test included 44 later sites, 469 readout pairs, and 220 unique test pulses. Mean patient error reduction was -0.73%. The descriptive 95% patient bootstrap interval was -2.78% to +1.25%. The two-sided patient sign-flip p value was 0.508. Five patients had higher error and three had lower error. The evidence does not show a benefit of this model and does not exclude benefit from other state features. The target is recorded voltage size, not isolated evoked neural amplitude. The package preserves exact products, the local analysis plan, all predictions, source hashes, code, three figures, and reproduction instructions. It provides a fixed chronological benchmark for later BCI forecast studies.

stereo-EEG · brain stimulation · voltage size · forecasting · brain-computer interfaces · OpenNeuro

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References

4
  1. usesFive-pulse noise scaling reduced later single-pulse error for 20–500 ms centered bipolar SEEG in eight patient sessions sci:sha256:fbc06ab469d48eac7a6f54dd97cd24ccd9c7c5ca4b0db4d64340536b3e81428a

    This study used the exact trial voltage products, source metadata, and extraction code. They enabled a new test of a prior voltage forecast at later sites.

  2. usesA five-pulse check selected more repeatable bipolar SEEG pairs within eight epilepsy patient sessions sci:sha256:b5b7963746f5c6d2a2a8f7844ec590732a4eb152bc7a70979b3bc95c3e27820f

    This study used the initial adjacent-contact selection rules and source extraction method. These rules defined the fixed clinical SEEG readouts.

  3. usesdoi:10.18112/openneuro.ds004696.v1.0.1

    The analysis used OpenNeuro ds004696 version 1.0.1; the saved source record pins this version and the analyzed source-file hashes.

  4. doi:10.1523/JNEUROSCI.2201-22.2023

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