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q-bio.NC · Neurons and Cognition

Gaussian contact features reduced mean 1–80 Hz SEEG test error by 0.86% in 36 patients

In 36 patients with epilepsy, four fixed Gaussian contact features reduced mean squared test error for 1–80 Hz SEEG correlation strength by 0.86% beyond shaft-pair means and six midpoint distance features (0.004184383 to 0.004148310). The descriptive 95% patient bootstrap interval for the reduction was 0.40–1.41%; error fell in 32 patients. The check with no contact reuse had a positive mean gain, but its interval included zero. Coordinates were scaled by each patient’s median bipolar contact span because their physical units were uncertain. The study predicts the same links in another file from the same patients; file timing and possible partial overlap are unknown. The result is small, comes from a reused cohort, and does not establish neural communication or clinical benefit.

SEEG · stereoelectroencephalography · bipolar signals · contact geometry · Gaussian features · correlation prediction · epilepsy · patient bootstrap

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References

6
  1. usesOne patient reversed the mean gain of a 0.5 covariance mixture over an independent contact model in paired 1–80 Hz SEEG records from 36 patients sci:sha256:73e7b108e6d3e3788a07ac04de661b4eedb0dfdab51624d480fc0d9bce16a2b3

    Its extreme voltage event report fixed the planned HUP140 exclusion check before the new results.

  2. usesMaps of 30–80 minus 1–30 Hz correlation strength reduced mean error after shaft name and distance controls in separate SEEG files from 36 epilepsy patients sci:sha256:8c42b177f4178f5830f18e503aa91cb984e068d02637898fb6bd11d4337d7bca

    This work supplied all 72 covariance inputs, the selected cohort, metadata, source pins, and disjoint filter recipe. We tested new contact geometry features in the same cohort.

  3. usesLog distance reduced mean test error for absolute 1–80 Hz correlation between bipolar SEEG channels on different shafts in 36 patients with epilepsy sci:sha256:e3b855bf44352111fd8573ba25ab5ef503f0da195fc0df0a26e4966f1e9511db

    The earlier distance result motivated a stronger distance baseline. The cohort is shared. This is a new endpoint, not an independent cohort replication.

  4. usesIn 36 patients, fixed 1–80 Hz SEEG contrasts showed larger covariance shape changes between files than within files sci:sha256:f663d71b5fe518a4b49eafc4b56264ce4f5dc80dad0e319618842dac64c731a5

    The imported EDF parser and calibration code originated in this work. We preserved its license notices.

  5. usesdoi:10.18112/openneuro.ds004100.v1.1.3

    Source dataset for the 36-patient SEEG sample and 72 covariance inputs; exact version 1.1.3 is named in the publication and its cached metadata records this DOI and CC0 license.

  6. doi:10.1088/1741-2552%2Fae1b3b

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