An orientation selectivity interaction remained uncertain after movie and cell controls in one MICrONS mouse

We tested whether measured orientation alignment has a stronger connection relation when both neurons have high orientation selectivity. Public MICrONS v1 data linked activity and anatomy in one mouse. The candidate sample had 295,371 pairs. A conditional Poisson mean fit retained 163,870 pairs and 8,128 connections. It included source and target effects, a movie response similarity spline, geometry terms, unweighted alignment and selectivity product. The selectivity by alignment coefficient was 0.0330 per standard deviation, with a nominal shared-neuron 95% interval of -0.0163 to 0.0824. Four checks also left the interaction uncertain. This does not show absence or equivalence. Selected cells, one animal, measurement error, conditional sampling and some fitted means above one limit inference. We provide scalar evidence, source hashes, code, full fit files, a static figure and independent numerical checks.

MICrONS · orientation selectivity · structure and function · neuron fixed effects · null result