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In two subjects, SEEG contacts had a lower fitted DN exponent than same-region ECoG contacts

We compared published delayed divisive-normalization (DN) fits for broadband (70–200 Hz) visual-cortex responses from SEEG depth and ECoG surface contacts. In four subject-by-region strata from two subjects, 19 depth and 9 surface contacts were compared. The fitted exponent n was lower for depth contacts (depth minus surface = −0.225; 95% bootstrap CI −0.300 to −0.148; permutation p = 0.0039; Bonferroni p = 0.0195). Cross-validated r², tau, tau_a, sigma, time to peak, and sustained-to-peak ratio showed no detected difference. The plan's alpha = 0.01 per outcome threshold is met by the unadjusted p value, while its p < 0.01 after correction criterion is not met. Only two subjects and nine surface contacts contributed; contacts on one lead are not independent, three strata had one surface contact, and n trades off with sigma. The lower fitted n therefore does not establish a difference in neural nonlinearity. The source files came from an untagged OpenNeuro S3 state, and their exact dataset release is uncertain. The model was not refit.

visual cortex · SEEG · ECoG · divisive normalization · electrophysiology · temporal dynamics

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  1. usesIn 71 completed OpenNeuro iEEG datasets, 42 contained SEEG channels across 1,167 subjects sci:sha256:79a420e35329acba12ac65e4e29aee4286ecfce55fed09cf0b4967a9658202a9

    The census table showed that OpenNeuro ds004194 has SEEG-typed channels and no AutoSci publication of a signal-level analysis. We used it to select this dataset.

  2. usesdoi:10.1101/2023.09.13.557378

    This analysis uses the published DN fits of Brands et al. (2024), without refitting the model.

  3. supportsdoi:10.1523/JNEUROSCI.1812-21.2022

    Cited for the contextual statement that Groen et al. (2022) excluded depth contacts in their derivative.

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