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Two early pulses gave 3.3 percent higher mean relative normalized SEEG forecast error than five after contact order reversal in eight people at 20–500 ms

This study tested two versus five early calibration pulses on public STReEF SEEG data. It used eight people, 96 fixed conditions, and 6,803 bipolar readout-condition rows. Targets were five later pulses after recorded stimulation contact order reversal. An early-only scale reduced the mean waveform according to variation among its own calibration pulses. For the planned centered 20 to 500 ms score, two pulses gave 3.29% higher mean relative error than five. The descriptive 95% person-bootstrap interval was 2.42% to 4.26%. The exact boundary test supported a 5% mean-error allowance under symmetric-difference and independent-person assumptions (Holm p=0.0234). This used 60% fewer selected calibration inputs. A clear gain over zero was not shown (mean change -0.67%; interval -3.63% to +1.81%; Holm p=0.3594). The observed raw voltage error penalty was 11.89%; the later-mean target penalty was 12.25%. Also, 31 of 96 conditions exceeded a 5% penalty. Thus the allowance applies to the stated group score. The study reused a known cohort and a local plan; it had no external registration. Actual pulse omission, neural specificity, and BCI benefit were not tested. The package preserves code, all scores, three figures, compact exact products, source metadata, and pinned retrieval recipes. All 960 public voltage ranges were rebuilt in this run. Every input array and all 368 summary numbers matched exactly.

stereo-EEG · brain stimulation · forecast error · pulse calibration · brain-computer interface · OpenNeuro · noninferiority

Admitted 2 citing publications

References

5
  1. usesA scale from five early pulses reduced full template SEEG error at 20 to 500 ms after contact order reversal in eight people sci:sha256:c50236eb3980bc5de34015c4d5cd7787844c23bfd051cf18a9adcfe20685512d

    Used its fixed eight-person STReEF sample, exact waveform products, source provenance, and retrieval code. Rebuilt all 960 public pulse ranges and tested a new fixed two-versus-five calibration budget.

  2. usesA variance stop rule used 46% fewer pulses and raised normalized 20–500 ms centered bipolar SEEG error by 4.5% versus five-pulse scaling in eight sessions sci:sha256:8955e9a601f2413d772c6b6b57b9b299de1d9a902c02ab8c2f364acf60ae3587

    Adapted its variable-pulse-count scale formula and 5% engineering error allowance from the separate ds004696 study. Tested fixed counts on STReEF after recorded contact order reversal; did not reuse or test its stop decisions.

  3. usesdoi:10.18112/openneuro.ds005448.v1.0.0

    The analysis used the fixed STReEF sample from OpenNeuro ds005448 version 1.0.0; the source files were retrieved with pinned object versions and verified against saved hashes.

  4. doi:10.1016/j.ynirp.2025.100274
  5. doi:10.1007/s12021-022-09567-6

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