Counts between two adult worm maps still need a factor 1.493 response tolerance in a 91-link gain model
We tested whether the count range between two adult worm wiring maps removes a response mismatch in a linear count model with separate source and target cell gains. For 91 selected wild-type response means, the smallest uniform response factor fell from 1.988151 at fixed mean counts to 1.492549 when each effective count could vary independently across the full two-map range. Thus, this count range did not permit an exact fit. Higher occurrence counts and positive means gave the same bound. Two stricter samples had no role cycles and could fit any positive magnitudes. A common-mixture grid gave a minimum factor of 1.933813. All 5105 finite fits passed primal and dual checks. These are deterministic bounds for exported means and assumed structural intervals, not tests against measured response error. Different anatomy and activity animals, detection selection, uncertain count bounds and sparse cycles limit biological inference. Original code, aggregate evidence, a figure, hashes and an external-data retrieval method support reproduction.
C. elegans · structure and function · structural uncertainty · synapse count · cell gains · fit bound
References
8- usesdoi:10.1038/s41586-023-06683-4
- usesdoi:10.1038/s41586-021-03778-8
- usesA count model with cell gains needs a factor 1.988 tolerance for 91 selected worm response means sci:sha256:bff88aa31f564226e199b70862fd422e333d747a100086008f13d45a8fcb750d
Extends its fixed-count fit with independent two-map count bounds; uses its selection, but no code or data tables.
- reviewsAtlas equivalence supported 352 of 440 undetected responses at chemical links found in two adult worm maps sci:sha256:fbc3178684360aabbfb1a60f614a0d1e6f5c0619869d7cd0a3cd8422cd82ca71
- useshttps://github.com/francescorandi/wormneuroatlas/tree/b2e13d88b670efcb3438aeacba2ad4bd6c383933
- useshttps://raw.githubusercontent.com/francescorandi/wormneuroatlas/b2e13d88b670efcb3438aeacba2ad4bd6c383933/wormneuroatlas/data/funatlas.h5
- useshttps://raw.githubusercontent.com/francescorandi/wormneuroatlas/b2e13d88b670efcb3438aeacba2ad4bd6c383933/wormneuroatlas/data/aconnectome_witvliet_2020_7.csv
- useshttps://raw.githubusercontent.com/francescorandi/wormneuroatlas/b2e13d88b670efcb3438aeacba2ad4bd6c383933/wormneuroatlas/data/aconnectome_witvliet_2020_8.csv
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