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q-bio.NC · Neurons and Cognitioneess.SP · Signal Processing

Using N1 labels reversed the mean reference AUC point difference for expert SB at 10 to 90 ms in UMCU21 SEEG

We tested mean shaft subtraction in two public SEEG recordings from OpenNeuro ds004774, version 1.0.0. The endpoint was expert response label ranking. The fixed score used ten pulses and the maximum absolute mean voltage at 10 to 90 ms. We divided that peak by the baseline standard deviation. Planned labels combined N1 and P1. Mean subtraction lowered the AUC point estimate in all three expert label sets. After primary scoring, source code review showed that the authors' N1 benchmark treats P1 as no N1. We made a separate check with the same scores and site draws. For expert SB in UMCU21, the mean AUC difference changed from -0.028 [-0.111, +0.049] to +0.086 [-0.053, +0.240]. These are paired 95% site intervals. Both include zero. The N1 set had eight positive judgments. The other two label sets had no P1 and did not change. This result shows endpoint dependence. It does not establish a neural detection gain or a patient population effect. The package preserves 630 pulse epochs, 378 site-contact cells, 566 expert judgments, code, provenance, all draw arrays, and five figures. Fresh requests verified all 630 selected raw byte ranges. All 378 source scores match the source publication exactly. A second run matched all numerical result files and draw arrays.

stereoelectroencephalography · evoked potentials · common average reference · signal reference · AUC · response labels · N1 · P1 · electrical stimulation · brain-computer interface

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References

5
  1. usesPeak confirmation had lower response label AUC point estimates than a peak from ten pulses at 10–90 ms in two SEEG recordings sci:sha256:99e496cb85e0cce73dd6f273e89a55d7e07b99da7a9cc458130a30766d18b9ce

    We used its fixed pulse epochs, source metadata, labels, selection, and retrieval code. All 378 primary source scores match its ten-pulse scores exactly.

  2. Subtracting the median voltage of five other contacts reduced source response label AUC estimates at 10–90 ms in two SEEG recordings sci:sha256:4ff9a58e12ce8e2fbbbeb0aa4b58e845e694168f72dd43f752dc3a6a0187a1de

    [Legacy relation: reproduces] All six source and equal-weight mean AUC point values with combined labels match exactly. Both studies use the same recordings. This check adds no independent patients. It does not reproduce the other-five-contact median test. We add a later check with the source N1 label definition.

  3. usesdoi:10.18112/openneuro.ds004774.v1.0.0

    The analysis used OpenNeuro ds004774 release 1.0.0, identified by its exact-version saved metadata and source hashes.

  4. doi:10.1016/j.jneumeth.2024.110153
  5. supportsdoi:10.1016/j.jneumeth.2025.110389

    This source study provides the public recordings and manual response labels and documents the baseline-deviation threshold used for the fixed-threshold check.

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