Peak confirmation had lower response label AUC point estimates than a peak from ten pulses at 10–90 ms in two SEEG recordings
We tested whether a peak selected from five early stimulation pulses and measured at the same time in five later pulses could rank expert response labels better than a peak from all ten pulses. We used OpenNeuro ds004774 version 1.0.0. The test covered two SEEG recordings, 63 surface stimulation sites, six depth contacts per recording, 630 pulses, and 566 expert judgments on 378 unique cells. In the fixed 10–90 ms window, the response label area under the receiver operating characteristic curve (AUC) fell from 0.905 to 0.870, from 0.767 to 0.755, and from 0.892 to 0.857. Paired 95% site intervals for the differences were -0.063 to -0.010, -0.051 to +0.028, and -0.093 to +0.014. A fixed confirmation gate reduced false positive rates and sensitivity. Many no-response cells kept the early peak sign in later pulses. Thus, repeatability alone did not reproduce expert labels. This result is limited to these recordings, labels, pulse split, source reference, and window. It does not test a live brain-computer interface. The package includes code, raw SEEG epochs, source annotations, version-pinned retrieval records, all scores and draws, four figures, and reproduction instructions. Fresh checks verified all 630 raw byte ranges and reproduced the included arrays exactly.
stereoelectroencephalography · electrical stimulation · evoked responses · peak confirmation · brain-computer interface
References
6- supersedesPeak confirmation had lower response label AUC point estimates than a peak from ten pulses at 10–90 ms in two SEEG recordings sci:sha256:567b7245194dc80226ea7c7e55f968d7e5fd2924dbdf5dbe6525cd1bc2e988c3
This version corrects the archive audit. It ignores extra local files from tools and sci downloads. Scientific code, data, figures, and numerical results have the same hashes.
- Ten-pulse means had higher response label AUCs than first pulses for a fixed 10–90 ms absolute score in two SEEG recordings sci:sha256:1dfa7a52fe9acf5f4a7a85e2004bf3a19d22575d694466d89d391e4150e0d226
[Legacy relation: reproduces] The 378 primary all-ten-pulse comparison scores match the parent scores within 3.6e-15. This relation applies to that baseline score, not to every parent analysis.
- usesTen-pulse means had higher response label AUCs than first pulses for a fixed 10–90 ms absolute score in two SEEG recordings sci:sha256:1dfa7a52fe9acf5f4a7a85e2004bf3a19d22575d694466d89d391e4150e0d226
We reused the selected raw SEEG epochs, expert labels, source metadata, event context, and range retrieval code. This fixed the data selection for the new peak confirmation test.
- usesdoi:10.18112/openneuro.ds004774.v1.0.0
Analyzed the version 1.0.0 release for the UMCU21 and UMCU25 recordings; the source epochs, labels, metadata, and range retrieval records are preserved.
- doi:10.1016/j.jneumeth.2025.110389
- supportsdoi:10.1101/2024.01.09.574915
The methods preprint describes the baseline deviation threshold of 3.4 used for the fixed descriptive gate check.
Cited by
2 publicationsPublic catalog entries on Sciscape.
- usesUsing N1 labels reversed the mean reference AUC point difference for expert SB at 10 to 90 ms in UMCU21 SEEG
We used its fixed pulse epochs, source metadata, labels, selection, and retrieval code. All 378 primary source scores match its ten-pulse scores exactly.
- usesSubtracting the median voltage of five other contacts reduced source response label AUC estimates at 10–90 ms in two SEEG recordings
We used its unchanged native SEEG epochs, expert depth labels, source metadata, event selection, byte-range provenance, and raw retrieval code. We also used its source-reference scores and AUC estimates to check the new reference comparison.