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A fixed test of repeat distances did not confirm shared tree rejection in six SEEG patients and 24 fMRI adults

We tested whether fixed relations between four sounds reject an additive tree in separate human SEEG and fMRI studies. Independent repeats supplied squared response distances. The score kept a minimum within each person and quartet before averaging. Under stable repeat means and zero cross-repeat error covariance, concavity makes its expected value nonpositive for a tree. Two patients and four MRI adults supplied development. A local code and list lock preceded tests in six other patients, sixteen B2021 adults and eight NH2015 adults. Each modality had a separate list of 128 quartets. The MRI list transferred by audited sound ID and clip name to the second MRI study. Mean scores were -0.066239, +0.220456 and +0.138247 in squared calibration site SD units. Their 95% person Student intervals were [-0.211332,+0.078853], [+0.173437,+0.267475] and [+0.093962,+0.182531]. All 24 MRI adults and one of six patients had positive scores. The fixed shared rule failed, p=0.853286. Alternate SEEG calibration blocks gave positive means. Keeping spatial means left NH2015 uncertainty across zero. These checks do not replace the primary result. Exact examples show that channel mixing, stable nuisance and one scalar can give positive squared-distance scores. Selecting an order from test noise also gave a positive simulation mean for a true tree. The contribution is an audited assay, a repeated-response benchmark and a negative cross-modal test. Clinical sampling, source selection, different cohorts and filters, fixed sounds, few electrical patients and repeat assumptions limit scope. The package preserves code, source versions and terms, local plans, all results, figures and repeat instructions. Original neural arrays remain external. No common neural geometry or cause is established.

human auditory cortex · SEEG · fMRI · representational geometry · tree metrics · independent repeats · negative result · public data

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References

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  1. usesSelected tree scores fell by over 25% in reserved MEG and IT fMRI tests in one 15-adult study sci:sha256:8ca227c963b1c7745debc3c77b9d4a7aafeaaa52eb09361feb3eaa180e41c954

    We build on its fixed tree tests and credit its exact heterogeneous-tree averaging limit. Our assay uses independent repeats and takes the minimum within each person.

  2. usesExact image trees did not ensure tree distances between category centers; shared EEG and fMRI rejection tests failed sci:sha256:2ee5c7ef28d2728eaebb909c3b1dc66ec6de397817751561685932888e113362

    Its category-center counterexample motivates testing individual sounds rather than category response centers.

  3. usesFor 165 fixed sounds, four-component models reduced repeat error in six SEEG patients and 24 fMRI adults sci:sha256:1ffb0217c831625cbe8fc949585c14c1f283f7e9f1b2113e69122af88fa9a59b

    We reuse its MIT source preparation code, source pins and cohort selection. We test a new endpoint and retain source-selection limits.

  4. usesdoi:10.1016/0095-8956(74)90047-1

    The established four-point condition defines the additive tree restriction.

  5. usesdoi:10.1371/journal.pcbi.1005508

    Independent-repeat inner products estimate response distances without the ordinary within-repeat distance bias under stated error conditions.

  6. usesdoi:10.1371/journal.pbio.3001675

    Original human SEEG study and processing description.

  7. usesdoi:10.5281/zenodo.6544488

    Public Rupp source data, version v1.1; exact Git and file hashes are preserved and source arrays remain external.

  8. usesdoi:10.1152/jn.00588.2020

    Original B2021 human fMRI cohort.

  9. usesdoi:10.1016/j.neuron.2015.11.035

    Original NH2015 human fMRI cohort.

  10. usesdoi:10.1371/journal.pbio.3002366

    Public author archive supplies the two fMRI releases and states that the 28 adults are unique.

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