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q-bio.NC · Neurons and Cognition

Contact exclusion raised fixed 20–100 ms SEEG power forecast error by a mean 22.7% across eight patients

We tested a fixed distance rule with public SEEG data from eight patients with epilepsy. The test used 93 stimulation conditions and 6,634 recording pair conditions. We forecast the later power ratio from earlier pulses at other stimulation sites. Removing all donors that used either test stimulation contact raised error in all eight patients. The mean patient relative increase was 22.7%. The patient bootstrap range was 11.9% to 34.0%. The spatial gain over the equal donor mean changed from 10.5% to −0.7%. An exact donor count control retained an 8.2% mean gain. Shared contacts also differed in distance and time. The result does not identify the cause. It supports contact exclusion as a useful test for stimulation map forecasts. This package contains source data checks, code, full scores, figures, and replay instructions.

stereoelectroencephalography · electrical stimulation · forecasting · contact exclusion · power · epilepsy

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References

6
  1. usesA fixed four-contact model gave 1.5% higher mean 20–100 ms SEEG power forecast error at excluded recording shafts in eight patients sci:sha256:95431a5050d8040a2e9a296fde791110e9355e6c2f658573ebfbc24067b8c8f6

    This work uses the compact pulse powers, native coordinates, selected events, source metadata, and pinned raw retrieval code. This run checked all 960 raw ranges and all 408,180 window powers against that input. The new analysis adds test contact exclusion and an exact donor count control.

  2. Fixed distance weights gave 1.6% higher mean relative SEEG power error at excluded shafts in eight patients sci:sha256:1c6b8bcedc82cbb2a0fde7f22417df13d8887c1f40cb02ef5595c33ded818472

    [Legacy relation: reproduces] A separate scalar implementation reproduced 48 patient score records from six prior distance rule variants. This work uses the same selected patient sample. It adds exclusion of both test stimulation contacts and exact enumeration of subsets with the same donor count. It is a new analysis of reused data, not an independent patient replication.

  3. usesGreater distance was associated with a smaller early window advantage in repeatable SEEG voltage at 96 conditions in eight patients sci:sha256:8ce49df0e874a8fe67c61d4467b06d1a1564be89d2f8ec47da539373586edbd8

    This publication is an earlier waveform statistics source in the preserved input chain. The present run retrieved its input through publication 338400ed-bf57-46db-98ab-03e719884214. This citation identifies indirect provenance. The chain adds no independent patient sample.

  4. usesdoi:10.18112/openneuro.ds005448.v1.0.0

    The analysis uses STReEF OpenNeuro ds005448 version 1.0.0 data.

  5. doi:10.1016/j.ynirp.2025.100274
  6. doi:10.1007/s12021-022-09567-6

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