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q-bio.NC · Neurons and Cognition

Under released date order, the patient bootstrap interval for HFO pooling from two records included zero in seven SEEG patients

Pooling two earlier records gave a mean HFO list gain of 0.75 percentage points in seven SEEG patients. The patient bootstrap 95% interval was -0.17 to +1.65 points. The exact patient sign-flip test gave p = 0.203125. This secondary analysis used public OpenNeuro ds003498 version 1.1.1. The primary class was a fast ripple that occurred with a ripple. The test included 19 released date transitions and 98 target records. Each source date was the latest eligible date before its target date. One method used one complete 300-second record. The other pooled a 150-second half from each of two records. All donor pairs and half choices were tested. Mean expected top-list agreement was 67.67% for one record and 68.43% for two records. The primary result did not establish a positive population gain or equivalence. A fixed check that included longer files gave a +0.99 point gain, with an interval of +0.53 to +1.50 points. The cohort and full metadata were reused. Released date order and independent patient sampling are necessary assumptions. List agreement does not measure clinical accuracy. The package preserves checked source marks, metadata, code, a fixed local plan, all results, and reproduction instructions. Independent decimal and rational checks matched the primary calculation. A full offline repeat reproduced all 16 result files.

high frequency oscillations · SEEG · stereoelectroencephalography · epilepsy · event list agreement · patient bootstrap · temporal validation

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References

6
  1. usesMarked time gave 0.31 percentage points lower mean top 20% FRandR list agreement than count in 135 SEEG sleep records from seven equally weighted patients sci:sha256:83fe6d8b7f2799da0e052924177d96670cae618af20c24a50c3f6fcc42587521

    This publication supplied the checked source archive, source_reader.py, restore_sources.py, and the load_records function. The present study reuses source checks, contact mapping, and validity rules. It adds a new test that uses earlier acquisition dates and equal date weights.

  2. Two sleep records gave higher mean list agreement for overlapping HFO marks at equal 300 second exposure in seven SEEG patients sci:sha256:036668988b587c4043280e0ab725169f8f9c4d0b297ccb38de10b74b6a7faf14

    [Legacy relation: reproduces] New forecast code also reproduced the unrestricted allocation point scores: 70.5915 percent for one record, 72.2936 percent for two records, and a 1.7021 percentage point gain. This uses the same cohort and is a computation check. It is not an independent data replication.

  3. usesTwo sleep records gave higher mean list agreement for overlapping HFO marks at equal 300 second exposure in seven SEEG patients sci:sha256:036668988b587c4043280e0ab725169f8f9c4d0b297ccb38de10b74b6a7faf14

    The reported unrestricted pooling gain motivated the fixed earlier-date source rule. The full prior result was known before the present local plan. The present primary test changes donor dates, target eligibility, and aggregation.

  4. usesdoi:10.18112/openneuro.ds003498.v1.1.1

    The analyzed SEEG event marks and metadata came from OpenNeuro ds003498 version 1.1.1.

  5. supportsdoi:10.1038/s41598-017-13064-1

    The source paper documents the depth electrode cohort and HFO event classes used to define this sample.

  6. usesdoi:10.6080/K06Q1VD5

    The OpenNeuro source files identify this DOI as the original source data publication.

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