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Distinct pulse products gave a negative energy estimate for 44 micro-SEEG contacts in one pig at 20 to 200 ms

We tested four spatial modes in public OpenNeuro ds004819 version 1.0.0. One pig supplied eight current blocks, 80 fit pulses, and 79 later test pulses. The main set had 44 contacts with source impedance numbers at most 1000. This numeric rule is not a validated contact quality limit. We compared bases fitted to individual early pulses and to ten-pulse means. Products of different test pulses estimated repeatable energy at 20 to 200 ms after spinal stimulation. The pooled total estimate was -18,699 squared EDF-number units. Its descriptive 95 percent range was -65,046 to 27,252, conditional on fixed bases and blocks. Six blocks had negative estimates. Thus, the main test did not support a retained-energy fraction. All 64 contacts gave a positive total and four-mode ratios near one. Twenty contacts above the source-number threshold contributed 92.4 percent of that signed total under the 64-contact reference. This sensitivity does not identify valid neural contacts. A negative estimate does not prove absence of an evoked response. We did not identify a better fit rule. The package preserves code, exact inputs, source pins, signed results, three figures, and instructions. All eight raw rebuilds matched exactly. All values in eleven analysis outputs matched in a fresh process.

micro-SEEG · stimulation · repeat products · spatial compression · response energy · jackknife · pig · signal processing

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References

6
  1. usesCross-pulse energy outside three fitted directions exceeded baseline at 20–100 ms in five SEEG sessions sci:sha256:991eea0a703c962b7e3cd4d2d757acc0d442c8ecbe9fd139d366ae446a26e906

    This work informed the use of products of different test pulses for fixed fitted directions. It used a different human dataset and different features. This study uses no data or fitted outputs from that work.

  2. usesProportional current scaling gave less prediction error than local interpolation from 20 to 150 ms for 36 micro-SEEG contact differences in one pig sci:sha256:2323d203ec8ca27ff44d222204c193913442149f392a27331cf121c06ef66cca

    This work informed the question about pulse-mean reliability. It tested prediction at excluded currents. This study includes all currents during calibration and tests spatial compression on later pulses. No results or model outputs were reused.

  3. usesA linear map from eight fixed contacts left a 0.91 mean error ratio for local voltage differences in eight current blocks from one pig. sci:sha256:03676cecb0d0cc09fc5e3608deeb0ea607a07512105e9a11416492128bbbdb39

    This study uses the eight exact input crop arrays, the pinned source manifest, source metadata, the EDF reader, and the source impedance diagnostic. It fits new bases and uses no parent model output.

  4. usesdoi:10.18112/openneuro.ds004819.v1.0.0

    The analysis used the raw recordings from OpenNeuro ds004819 version 1.0.0; exact-version metadata records the dataset as CC0.

  5. doi:10.1038/s41586-019-1346-5
  6. supportsdoi:10.1038/s41467-023-43727-9

    This source paper describes the pig experiment as cortical recording under anesthesia during direct spinal stimulation.

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