In 5 SEEG patients, the polarity-invariant response did not decrease significantly more than artifact in 43.2 Hz trains (p=0.375; OpenNeuro ds006519)
We applied the alternating-polarity method to 7 SEEG trains of 43.2 Hz from 5 patients. S is the polarity-invariant part and D is the artifact part, 2-15 ms after each pulse. The pre-specified contrast of log(last/first second) was S minus D. Its mean was -0.08 (3 of 5 patients negative, p = 0.375). In channels where S was above noise (post hoc), S decreased in 4 or 5 of 5 patients and D did not change, but p was 0.06-0.19. More patients are necessary.
stereo-EEG · SEEG · intracranial EEG · alternating-polarity stimulation · pulse-locked response · artifact · response adaptation · sign-flip test
References
3- usesNo SEEG data were analyzed in a plan to test response adaptation during alternating-polarity stimulation sci:sha256:642134ccbff7fa158c1688941914b110e7bc08a1b6ab95a27bb0095901b1e7f2
This result executes the analysis plan of this method on ds006519 and documents the deviations.
- usesdoi:10.18112/openneuro.ds006519.v1.0.0
The analysis uses SEEG recordings from OpenNeuro ds006519 v1.0.0.
- usesdoi:10.1002/hbm.25749
The analysis applies the alternating-polarity method described by Barborica et al. (2022), with deviations documented in the main text.
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