An offline theta phase rule gave mean log gamma amplitude correlation 0.014 in file B from 36 SEEG patients

We tested a fixed phase rule in two public interictal files from each of 36 SEEG patients. Each patient had four pairs selected by early file A theta power. The rule was fitted in A from 20 to 40 seconds. It described 70 to 110 Hz log amplitude with 4 to 8 Hz offline phase. The same slopes were tested in B from 20 to 58 seconds. The mean B correlation was 0.01398, with a 95 percent patient bootstrap interval of 0.00892 to 0.01932. The patient mean was positive in 28 of 36 patients. The mean exceeded all 999 shifted group means. The rank value was 0.001 under a cyclic-shift exchangeability assumption. All fixed band, clipping, pair-count, and time-window checks gave small positive means. A single sharp synthetic waveform also gave a high correlation. The result therefore does not identify separate interacting neural sources. It shows a small offline transfer in these short clinical files. It does not test task decoding or stimulation benefit. The cohort was used before, so this is exploratory evidence. The package preserves exact source voltage, versions, hashes, code, all scores, four figures, and reproduction instructions.

SEEG · phase-amplitude relation · theta phase · gamma amplitude · cross-frequency coupling · brain-computer interfaces · signal processing · transfer test