An early theta phase model reduced later log gamma error in two of seven SEEG rest records
We tested whether early theta phase terms reduce later log gamma amplitude error beyond theta amplitude. We used 28 fixed bipolar pairs from seven public SEEG rest records in OpenNeuro ds006065 v1.0.0. Each pair used 2 to 58 seconds for fitting and 122 to 238 seconds for testing. The mean relative error decrease was 0.134%. The descriptive 95% person bootstrap interval was -0.086% to 0.492%. Two of seven person means and seven of 28 pair means were positive. The exact two-sided sign-flip value was 0.8125. The observed mean exceeded all 999 shifted phase means under a shift-invariance assumption. This control tests phase alignment, not a consistent gain against the amplitude baseline. The filters use future voltage. The result does not establish neural coupling, an optimal stimulation phase, or a live interface benefit. The package preserves exact source-verified traces, features, code, coefficients, predictions, figures, and complete numeric replay checks.
theta phase · gamma amplitude · stereoelectroencephalography · SEEG · phase-amplitude coupling · transfer learning · calibration · brain-computer interface
References
5- usesAn offline theta phase rule gave mean log gamma amplitude correlation 0.014 in file B from 36 SEEG patients sci:sha256:2504d262f6503ed277a0715800795ee9b1aad97b318f8e2f672585d86c2d9611
We use its offline phase-amplitude transfer result as the scientific comparator. That study tested correlation in another cohort. The present study tests added mean squared error reduction beyond theta amplitude in seven rest records, so it does not reproduce or challenge the earlier correlation finding.
- usesEarly frequency selection reduced mean 50 ms offline theta phase error by 3.55 degrees in seven SEEG rest recordings sci:sha256:5c3ae075960de0774e0fcc176ee07a5e3c9a353d86238f1e49023a23aa4d2bfa
We used all seven exact voltage archives, all 28 fixed early-selected pairs, source metadata, and fixed byte-range hashes. Fresh version-pinned prefix downloads verified every selected voltage sample. A separate Welch calculation repeated the pair choices.
- usesdoi:10.18112/openneuro.ds006065.v1.0.0
Analyzed dataset: OpenNeuro ds006065 version 1.0.0; saved metadata matches this exact version and records CC0.
- doi:10.1038/s41467-025-59417-7
Background study that motivates testing whether a stimulation phase target remains useful after calibration.
- doi:10.1371/journal.pone.0167351
Background evidence on waveform shape as a source of apparent phase-amplitude relations.
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