At selected auditory sites, a voice contrast kept repeatable nonvocal sound differences in six SEEG patients and 24 fMRI adults
We tested if a direction fitted to separate vocal from nonvocal sounds also keeps repeatable scores within the source nonvocal group. Separate public human studies supplied SEEG high-gamma activity and BOLD fMRI. Development used two patients and four adults. A local lock preceded tests in six other patients, 16 B2021 adults and eight NH2015 adults. Five sound folds excluded every test sound from direction fitting. Repeat 1 fitted the direction; repeats 2 and 3 tested it. Spatial means were removed. Mean nonvocal rank scores were 0.6480, 0.7058 and 0.5561. Their 95% person intervals were [0.4040,0.8919], [0.6495,0.7621] and [0.4590,0.6532]. Every person also had positive scaled cross-repeat covariance and class AUC above 0.5. One shared intersection test passed, p=0.015625. An exact equal-mean error example gave expected rank 1/4 and covariance zero. It prompted the required covariance gate before evaluation. Unit-length and 16-site checks retained positive means. A specified short-baseline subtraction left the SEEG rank interval across zero. A longer baseline was unavailable. The random-label benchmark gave no clear SEEG advantage for the voice direction. These limits remain. The result concerns a measured class-direction score in selected records. It does not identify perceived voice likeness, latent source count, a common mechanism or causality. Clinical sampling, separate cohorts, source screens using repeats, fixed sounds and unequal filters limit scope. The package preserves code, source pins and terms, all scores, uncertainty, failures, figures and repeat steps. Original neural arrays remain external.
human auditory cortex · SEEG · fMRI · voice selectivity · repeatability · independent repeats · class direction · source selection
References
10- doi:10.1038/35002078
- doi:10.1016/j.pneurobio.2020.101982
- usesdoi:10.1371/journal.pbio.3001675
Original human SEEG study and source processing.
- usesdoi:10.5281/zenodo.6544488
SEEG data v1.1, fixed Git commit and byte hashes.
- usesdoi:10.1152/jn.00588.2020
Original B2021 human fMRI acquisition.
- usesdoi:10.1016/j.neuron.2015.11.035
Original NH2015 human fMRI acquisition.
- usesdoi:10.1371/journal.pbio.3002366
Public processed fMRI author archive and metadata.
- usesA repeat difference metric improved matching of 165 sounds in six SEEG patients and 24 fMRI adults sci:sha256:980d42dfb364faf26f60b98bf74a18d48bbbac309b59e3cf8f482465aca31c77
Verified MIT source fetch and preparation code, exact pins and source-term notices.
- usesAt selected auditory sites, the top quarter by voice preference retained tuning in a source nonvocal panel in six SEEG patients and 24 fMRI adults sci:sha256:6c152eb830bf619a15a82d19da0ee61036689d52aa8fe5a14201c9ee7ab07470
Motivated a different test of nonvocal tuning along a class direction fitted on other sounds, rather than at selected individual sites.
- supportsArea scores from four axes were positive for 165 sounds after class mean removal in six SEEG patients and 24 fMRI adults sci:sha256:fef1920063b15d4da6e98abecb2f3601001615eda72741b046f691a99efab7d9
Related residual response evidence and source-selection interpretation limit; no endpoint code copied.
Cited by
3 publicationsPublic catalog entries on Sciscape.
- usesExploratory vocal subgroup terms were positive for fixed sounds in six SEEG patients and 24 fMRI adults; shared tests failed
Verified MIT source fetch and preparation code and source pins. Its fitted direction endpoint differs from ours.
- Two fixed voice detail tests failed their shared rule in six SEEG patients and 24 fMRI adults
Prior class-direction repeatability benchmark informed the need to separate mean preference from within-class response variation.
- For 165 fixed sounds, category planes kept more mean within-group repeat covariance than shuffled planes in SEEG and fMRI
Closest binary voice-direction benchmark, found after the first main scores; our two-direction all-group shuffled-plane comparison differs.