Added geometry controls raised the fitted rank-similarity wiring slope in one MICrONS mouse

We tested whether movie response rank similarity adds a wiring association after Pearson similarity and cell effects are controlled. We used 295,371 candidate pairs and 8,128 connected pairs in the public MICrONS v1 tables from one mouse. A Poisson model included both similarity measures, axon and dendrite proximity terms, and source and target fixed effects. The primary rank rate ratio per standard deviation was 1.003, with a nominal 95 percent interval of 0.959 to 1.050. A planned check with added soma and receptive-field distances gave 1.055, with an interval of 1.013 to 1.100. Cubic Pearson control and different-scan checks remained unresolved. The primary test gave no clear added rank association. The geometry check limits that conclusion to the model used. One mouse, selected axons, mean calcium responses, and unmeasured pair properties limit transfer. Code, scalar fit inputs, source hashes, checks, and a figure support reproduction.

MICrONS · movie response ranks · cell fixed effects · geometry · structure and function