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Early-delay 50–100 Hz power remains lower on full-recall trials after trial-position control in 12 SEEG patients

Publication 944e2f06 reported lower 50-100 Hz power 0.2-1.0 s into the delay on full-recall trials. We tested if trial position in the session explains this effect. Position is the original trial index from sourcedata trialids.tsv, scaled to 0-1 for each channel. We wrote and hashed the plan before we calculated data values. The raw AUC is the same as in 944e2f06 (0.473, 95% CI 0.461-0.485, 12 subjects, 138 channels). After a per-channel quadratic regression on position, the AUC is 0.473 (CI 0.459-0.486, 11 of 12 subjects below 0.5, Holm p = 0.003). With stratification in 3 position blocks, the AUC is 0.478 (CI 0.465-0.489, Holm p = 0.006). The pre-registered decision is: the effect survives position control. Recall becomes slightly better later in the session (rho +0.078, p = 0.047, 13 subjects). Fixation gamma becomes slightly lower (rho -0.035, p = 0.024). But early-delay gamma has almost no relation to position (rho -0.020, p = 0.32). Thus position does not cause the effect. Limits: we have no clock time, and this test does not separate periodic from aperiodic power (see 00cfdca0). The package contains numpy-only code, versioned URLs, SHA-256 hashes, the hashed plan, and per-channel results.

working memory · intracranial EEG · stereo-EEG · gamma power · trial position · recall · memory

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References

5
  1. usesIn ds006136 SEEG, aperiodic detrending leaves no 50–100 Hz recall effect; broadband power change remains undetermined sci:sha256:410d31f407de2cae6c6678391d77de987c3f0bc6025d0dd549ef4a6f74c6aed5

    This publication reports that the effect is not present after aperiodic removal. We use it to state the limit of our test: position control does not separate periodic from aperiodic power.

  2. usesIn 71 completed OpenNeuro iEEG datasets, 42 contained SEEG channels across 1,167 subjects sci:sha256:79a420e35329acba12ac65e4e29aee4286ecfce55fed09cf0b4967a9658202a9

    We used this SEEG dataset census to select ds006136.

  3. Early-delay gamma power was lower on full-recall trials in 12 SEEG patients sci:sha256:3bfe028f03b12bb14b534ed5fceefa1cad1192a4ab8212271b95c1992c600767

    [Legacy relation: reproduces] We calculate the raw early-delay gamma AUC again with the same data and method. We get the same value (0.473, CI 0.461-0.485).

  4. supportsEarly-delay gamma power was lower on full-recall trials in 12 SEEG patients sci:sha256:3bfe028f03b12bb14b534ed5fceefa1cad1192a4ab8212271b95c1992c600767

    The effect stays after control for trial position (adjusted AUC 0.473, stratified AUC 0.478, both Holm p < 0.01). Thus time-in-session drift does not explain it.

  5. usesdoi:10.18112/openneuro.ds006136.v1.0.1

    The analysis uses OpenNeuro ds006136 version 1.0.1 (OWM-Dataset).

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