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Supplied ripple overlap marks had a higher mean local 0.5 to 2 Hz phase score in 14 sleep records from eight SEEG patients under block timing controls

We compared supplied ripple marks with and without fast-ripple overlap in public SEEG data from OpenNeuro ds003498 1.1.1. A plan saved before phase analysis selected 15 sleep records from eight patients. The primary test used 75 pair-record cells and local 0.5 to 2 Hz phase. We corrected pairwise phase consistency with 999 timing controls in 28-second blocks. Patients had equal weight. The mean class difference was 0.169953. Its descriptive 95 percent patient bootstrap interval was [0.105362, 0.223012]. The two-sided patient sign-flip p value was 0.015625. Overlap marks had a higher mean local score in the tested records. The descriptive patient interval did not include zero. We report every patient and all five planned sensitivity tests. The score can reflect sharp waves and filters. It does not identify a neural state or validate pathology. The SEEG scope uses source depth-implant descriptions despite ECOG channel labels and assumes matching source patient numbers. The package preserves 50 Hz voltage, mark tables, source hashes, raw retrieval instructions, code, control scores, figures, and a byte-identical offline rebuild.

intracranial EEG · SEEG · high frequency oscillations · ripple marks · fast ripples · pairwise phase consistency · slow-wave sleep · phase coupling · epilepsy

Admitted 2 citing publications

References

6
  1. usesA one second count cap gave no mean list agreement gain for overlapping HFO marks in seven SEEG patients sci:sha256:d9a5fbb15c44f6c91fbd65207296fc277baaa4af755ad3b9e3805eb6d083ef40

    We used its pinned ds003498 source table archive, resolved BrainVision headers, raw object keys, and channel aliases to retrieve and validate the inputs. Our phase code, scores, and patient tests are new.

  2. usesdoi:10.18112/openneuro.ds003498.v1.1.1

    Source voltage, supplied marks, channels, and headers for OpenNeuro ds003498 version 1.1.1.

  3. supportsdoi:10.1038/s41598-017-13064-1

    Source study for the detector mark classes and depth-implant descriptions used to define the tested patient scope; its clinical outcome result was not retested.

  4. doi:10.1111/epi.13912

    Background evidence on ripple phase coupling during sleep in a different cohort and with a different method.

  5. doi:10.1016/j.neuroimage.2010.01.073

    Source for the pairwise phase consistency definition and its usual independent-observation interpretation.

  6. doi:10.1016/j.jneumeth.2008.01.020

    Background on sharp waveform edges producing apparent relations between frequency bands.

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