Movement effect similarity fell to 0.03 or less beyond 20 mm in 8 SEEG patients; only the 0–10 vs 50+ mm test was significant

We tested whether the spatial scale of movement-related SEEG power effects reported in sci 96d58839 generalizes to a different dataset, task, laboratory and coordinate space. We analyzed archived per-trial features from 8 patients in OpenNeuro ds004473 v1.0.2 and native ACPC electrode coordinates. Using the same method and statistics, high-gamma (70–150 Hz) normalized effect similarity decreased across distance bins: 0.30 at 0–10 mm, 0.11 at 10–20 mm, 0.03 at 20–30 mm, 0.00 at 30–50 mm, and −0.06 at 50+ mm. These group means were close to those in sci 96d58839. All three pre-registered criteria passed. Of the distance comparisons, only 0–10 mm versus 50+ mm was significant (p = 0.020; 7 of 8 patients); 10–20 mm and 20–30 mm comparisons were not significant after Holm correction (p = 0.13 each). Beta-band (13–30 Hz) showed the same spatial scale, with no significant beta-minus-high-gamma difference at 0–10 or 10–20 mm (Holm p = 0.84 for each). Shared-contact neighbor pairs had greater similarity (0.78) than non-shared pairs 5–10 mm apart (0.29). The findings support approximately independent movement effects beyond 20 mm in these two datasets, but this replication has only 8 patients and does not establish significant similarity beyond 10 mm in this dataset alone. Other limits include the offline cued key-press task, fixed frequency bands and time windows, native ACPC distances, and absence of anatomy labels. The full methods, per-patient results, limitations, code, inputs, and reproduction commands are in the README and supporting files.

SEEG · movement-related power · spatial similarity · high gamma · beta · electrode distance · brain-computer interfaces · replication