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q-bio.NC · Neurons and Cognitioneess.SP · Signal Processing

Spatially adjusted 1 to 80 Hz SEEG treatment alignment gave outcome AUC 0.533 within therapy in 32 ds004100 patients

We tested whether treatment of sites with stronger spatially adjusted SEEG connections related to the source surgical outcome. We used OpenNeuro ds004100 version 1.1.3. The fixed score used 1 to 80 Hz bipolar signals, shaft-pair means, log distance, and treated-spared ranks within electrode shafts. The primary cohort had 32 patients. Outcome AUC within therapy was 0.533. The 95% patient bootstrap interval was 0.316 to 0.724. The exact two-sided test gave p = 0.779. The test assumes exchangeable outcome labels within therapy, with counts fixed. Scores agreed across the two source files, but their time separation was not verified. The result does not establish clinical value or the absence of outcome information. The package preserves all inputs, code, provenance, exclusions, and planned checks. Fresh retrieval of all 72 excerpts gave 648 covariance arrays that exactly matched the archived arrays.

stereoelectroencephalography · epilepsy · functional connectivity · treatment alignment · surgical outcome · spatial adjustment · AUC · intracranial EEG

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References

7
  1. usesBipolar 1–80 Hz SEEG correlation magnitude maps had positive correlations between file excerpts after signal, shaft pair, and log distance controls in 36 epilepsy patients sci:sha256:36170aff18fbecc7f57d9bf3c205be69a8ce1d45617c7e9600a74df38e629542

    Uses the 72 block covariance files, pinned source metadata, and EDF rebuild code. These inputs permit new spatially adjusted treatment scores and a patient outcome test. All covariance arrays were checked against fresh raw source retrieval.

  2. usesAfter signal and shaft pair controls, 1–80 Hz bipolar SEEG correlation magnitude between shafts had negative fitted coordinate distance slopes in all 36 tested epilepsy patients sci:sha256:c00ccb31868a25e0564b56ac6efac067acd957bb3bfeb7e0e5f340e3618bbca7

    Uses the covariance reader and bipolar conversion functions preserved in inputs.py. These functions reconstruct correlations and electrode geometry from the block covariance arrays.

  3. usesFixed gamma treatment overlap gave outcome AUC 0.380 within therapy groups in 36 public SEEG patients sci:sha256:6ec7b4751a2b2ae0cb934eb2800dae17c8e80de8520d910c9795ef52e6156812

    Uses the exact conditional rank test and patient bootstrap code. The present signal score is different. The common cohort is not an independent replication.

  4. usesIn 36 patients, fixed 1–80 Hz SEEG contrasts showed larger covariance shape changes between files than within files sci:sha256:f663d71b5fe518a4b49eafc4b56264ce4f5dc80dad0e319618842dac64c731a5

    Uses the EDF parser and range retrieval code as an earlier source of the rebuild method. License notices and pinned retrieval records are preserved.

  5. usesdoi:10.18112/openneuro.ds004100.v1.1.3

    Source dataset, exact version 1.1.3, for SEEG signals, treatment marks, and patient outcomes.

  6. doi:10.1088/1741-2552%2Fac90ed
  7. doi:10.1111/epi.18128

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