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Under exchangeable outcome labels within therapy, a test did not detect a mean group difference in gamma treatment ranks from two 60-second SEEG records in 36 patients

We tested a fixed gamma power rank score in 36 patients from OpenNeuro ds004100, version 1.1.3. Each patient had two 60-second SEEG records. The score ranked treated contacts against untreated contacts. We compared source outcome S with F within ablation and resection groups. The mean S minus F contrast, weighted by therapy group size, was -0.0293. The 95 percent patient bootstrap interval was -0.1479 to +0.0917. A label test within therapy gave p = 0.66236, under outcome exchangeability. The test did not detect a mean group difference. The interval permits effects in either direction. The score choice came from earlier onset-label work in this cohort. This is a secondary outcome study, not independent score validation. The package preserves all 36 spectra, clinical labels, patient scores, code, test draws, source versions, raw examples, checks, and reproduction instructions.

stereoelectroencephalography · SEEG · gamma power · epilepsy surgery · treatment outcome · contact ranking · permutation test

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References

3
  1. usesCommon average reference raises median relative gamma rank agreement in two 60 s SEEG records from each of 36 HUP patients sci:sha256:3f5f9f6ae779730a7bf70359ae9ddc56a5032c2e8abdb97c0cf3c127d6082e74

    This work supplied the original two-record SEEG spectra, contact quality rules, EDF retrieval code, and Welch method through the direct input archive. We preserved its code and source records. We checked two raw records with a separate decoder and SciPy spectrum calculation.

  2. usesDivision by total power lowered gamma AUROC in paired 60-second SEEG samples from 35 patients when higher scores marked seizure onset contacts sci:sha256:c83c25b21f95628d5ea3494c73122433aa202d4dcc652648cb0dd6fec9e495c5

    We used its archived absolute gamma features, all 36 patient spectra, source clinical metadata, and preserved retrieval records. We added a fixed patient outcome test within therapy groups. The new package preserves these inputs and checks their hashes.

  3. usesdoi:10.18112/openneuro.ds004100.v1.1.3

    The study used the 1.1.3 HUP iEEG dataset for source metadata, clinical labels, and SEEG records; cached version metadata records this exact dataset DOI and CC0 license.

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