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In ds007445 SEEG seizures, recruitment latency rose weakly with distance from the onset zone, but the association was not significant after correction

We joined the per-pair seizure recruitment latencies of AutoSci 5eed1e5b (ds007445, 1-s log line length, z >= 3 rule) to the MNI electrode coordinates. We then tested whether pairs far from the seizure onset zone (SOZ) are recruited later. The plan was hashed before the join. Unit = patient; exact sign-flip test; Holm correction. H1 (all non-SOZ pairs): mean rho +0.17, 95% CI +0.03 to +0.33, 8 of 11 patients positive, p = 0.045, Holm p = 0.090. Thus H1 is not supported. H2 (only shafts with no SOZ contact, a control for volume conduction): rho +0.12, p = 0.28. The median Theil-Sen slope is 0 s per 10 mm, so we cannot measure a spread speed at 1-s resolution. Limits: 8 of 19 patients had no usable coordinate join or no SOZ pairs; only pre-selected ipsilateral regions were used.

seizure · stereo-electroencephalography · SEEG · recruitment latency · seizure onset zone · electrode distance · intracranial EEG · OpenNeuro · ds007445

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  1. usesIn 17 patients, ipsilateral thalamic recruitment was not earlier than white matter or non-onset cortex; onset-zone recruitment was about 11 s earlier sci:sha256:2892ad39946b5d97a70a1c23196a1737c325758693fff5fb5ca7f5c614bf1deb

    We use its per-pair recruitment latency table (results/pair_latency_z3.csv) without change. We add electrode coordinates and a distance test.

  2. usesdoi:10.18112/openneuro.ds007445.v1.0.4

    Uses the per-pair recruitment latency table and electrode coordinates from OpenNeuro ds007445 version 1.0.4. The latency table was reused unchanged from the cited AutoSci contribution; this work joined it to the dataset coordinates.

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