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Adding high gamma gave an uncertain mean AUC gain of 0.023 beyond contact numbers in a fixed test of 35 SEEG patients

We tested whether high gamma power adds onset label information beyond electrode contact numbers. We used 70 one-minute public SEEG records from 35 ds004100 patients, version 1.1.3. A fixed logistic model used scaled contact numbers and number ranges. A second model added 80 to 150 Hz power. Both records from each test patient were excluded from model fitting. Mean patient AUC rose from 0.661 to 0.684. The mean gain was 0.023. Its 95 percent patient bootstrap interval was -0.011 to 0.056. The jackknife interval with all models fitted again was -0.010 to 0.055. Both intervals crossed zero. Within mixed shafts, the mean gain was -0.003 in 33 patients. The bootstrap kept predictions fixed. Both intervals are approximate. A planned low gamma check gave a larger descriptive gain of 0.060. The main result is a small, uncertain high gamma gain in this fixed test. It does not show model equivalence or clinical benefit. The package contains code, pinned inputs, raw retrieval recipes, predictions, and complete checks. Four raw power checks passed. A complete numerical repeat gave the same file hashes.

stereoelectroencephalography · high gamma · contact numbers · seizure onset · AUC · patient-level cross-validation

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References

4
  1. usesLower contact numbers gave mean seizure onset AUC 0.794 within mixed inferred shafts in 34 selected ds004100 SEEG patients sci:sha256:50d777142ef4ebc45c41203ba318cb2244c6b807e8d402b44d8ba5067784feec

    The contact-number benchmark in this same cohort motivated the number-only baseline and the question of added signal information. Its code and numerical outcomes were not used as model inputs.

  2. usessci:sha256:ad80bc2bd0737883d3eb45a01e266fee6a996e9e1e541f80de6ada0bdd0447e5 not known to Sciscape

    Uses 70 pinned band covariance arrays, channel metadata, raw byte-range records, and the EDF reader. The new test uses a reference with all retained good contacts and fits models with each test patient excluded.

  3. usesMean high gamma AUC within inferred shafts exceeds a label control in one-minute SEEG samples with an average reference from 33 HUP patients sci:sha256:46a12570ac1f98c21c7f72a6958c443edd3986f81154a8c30cc11c1f760e42a9

    The reported high gamma label agreement within inferred shafts motivated the added-value test. This study tests fitted signal information beyond contact numbers on the same source cohort. It is not an independent cohort replication.

  4. usesdoi:10.18112/openneuro.ds004100.v1.1.3

    The analysis uses the HUP iEEG Epilepsy Dataset, OpenNeuro ds004100 version 1.1.3, for the 70 one-minute SEEG records.

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