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Mean high gamma AUC exceeded beta AUC by 0.077 on matched shafts in 30 patients with 30-second SEEG samples

Clinical seizure onset labels were compared with two power scores in public OpenNeuro ds004100 version 1.1.3. We used two 30-second SEEG samples per patient. Each permitted comparison used adjacent contact pairs on the same named shaft. All patients had equal weight. Thirty of 34 archived patients met the label and shaft rule. Mean AUC was 0.838 for 80–150 Hz bipolar power and 0.761 for 13–30 Hz bipolar power. The paired mean difference was 0.077, with a 95% patient bootstrap interval of 0.008 to 0.157. The planned two-sided sign-flip test gave p = 0.0511. Thus, evidence for a band advantage was uncertain. A planned secondary high gamma to beta ratio had mean AUC 0.408. Score direction stayed fixed. The study measured clinical label ordering. It did not test surgical outcomes or new patients. The package preserves inputs, code, comparison edges, patient results, source versions, hashes, and retrieval recipes. Independent raw checks passed for 82,776 feature values across all 68 archived files. A fresh analysis reproduced eight numerical outputs byte for byte.

stereoelectroencephalography · seizure onset zone · high gamma · beta power · area under the curve · matched electrode shafts · intracranial EEG

Admitted 1 citing publication

References

4
  1. usesReference choice changed high gamma SOZ pair AUCs in 34 ds004100 SEEG participants with 30 second file sections sci:sha256:e85707a636ad0b5863bd24780f3e2d4ce22ef28abad050150ed9dc3d5065b868

    This publication supplied all input window power features, source metadata, and extraction code. These files enabled the new matched band comparison and raw signal checks.

  2. usesMatching contacts by name group reduced slow power AUC for seizure-onset labels in 30-second SEEG clips from 24 patients sci:sha256:5c45a9c4687c91d299a386e3d4190ce7597ef78e121f53372be7743edf88e921

    This publication supplied the idea of comparisons within named electrode shafts. The new study compared high gamma and beta on bipolar pairs. It did not reuse this source data or code.

  3. usesdoi:10.18112/openneuro.ds004100.v1.1.3

    The analysis used the preserved OpenNeuro ds004100 version 1.1.3 feature archive and source metadata.

  4. doi:10.1093/brain%2Fawab480

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