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q-bio.NC · Neurons and Cognitionstat.ME · Methodology

Fixed SEEG ranges showed no clear increase in excess same-side misses across shafts at 20–500 ms after pulses in eight people

We tested fixed SEEG size ranges at 83 stimulation sites in eight people with epilepsy, using five selected late pulses per site. In the 20–500 ms window, the excess of same-side misses across shafts was 0.662 percentage points, compared with 0.180 points in the −980 to −500 ms baseline window. The equal-person mean paired change was +0.482 points; its descriptive 95% person bootstrap interval was −0.313 to +1.703 points, and the exact two-sided person sign-flip reference value was 0.695. Three of eight people had a positive change. The result does not show a clear increase and does not establish that the change is zero. Omitting person 05 changes the mean to −0.085 points. An exact independent-shaft-order reference preserves dependence among pairs on each shaft. The study does not establish a neural cause or a live brain-computer interface benefit.

SEEG · electrical stimulation · brain-computer interface · range coverage · same-side misses · shaft dependence · independent-order reference · epilepsy

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References

4
  1. usesFive later pulses did not show higher SEEG size correlation across shafts at 20–500 ms than before stimulation in eight sessions with readouts selected from five early pulses sci:sha256:3e568cd9997feedb9652f1ade1733ba15c832a7040976086282aa09650536328

    This earlier result supplies scientific context. It tested log size correlations across shafts in the same eight source sessions and did not show a clear increase after stimulation. The present audit tests failures of fixed ranges and uses all retained recording pairs in its main score. It uses no inputs or code from this earlier correlation package and is not an independent replication.

  2. usesJoint ranges for 20–500 ms SEEG size covered all retained pairs in 77.2 percent of later pulses on average across eight sessions sci:sha256:d9c7c1c9a0076a833425327e2ff6632ea883a25fbfa68b6a99d537b8e7124202

    This study uses all 25 compact input files, the unchanged source extraction code, data instructions, and source provenance from this publication. It keeps the fixed range rule and selected pulses, then adds a cross-shaft miss alignment audit and a paired baseline comparison.

  3. usesdoi:10.18112/openneuro.ds004696.v1.0.1

    The analysis uses trial voltage arrays derived from OpenNeuro ds004696 version 1.0.1.

  4. doi:10.1523/JNEUROSCI.2201-22.2023

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