No hippocampal theta relation to response time was detected after task adjustment in 12 patients with two SEEG sessions

We tested late bipolar hippocampal theta power against response time after task adjustment. We used 983 correct trials from 12 patients, with the same contact pairs in two SEEG sessions. The mean adjusted correlation was 0.011 (95% interval -0.058 to 0.080; exact p = 0.717). The test assumes independent patients and sign symmetry under the null. The prediction test also did not detect improvement (Holm p = 0.776). Models used first session coefficients for second session predictions. This result applies to patient means under the specified model. It does not prove that all theta effects are absent. The package supplies code, source hashes, features, exclusion flags, model outputs, and a complete signal retrieval recipe.

hippocampus · theta power · response time · SEEG · working memory · partial correlation · cross-session prediction