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Separate thresholds at five checks raised background calls from 29.7% to 53.8% at 86 selected SEEG sites in eight patients with three calibration pulses

We tested repeated response checks after known stimulation pulses. The public source was OpenNeuro ds004696 version 1.0.1. We reused 86 selected contact differences in eight patients. Five pulses fit each reader. Three later background paths set its thresholds. The test had 353 later pulse pairs. Each patient had equal weight in the mean. One final check called 29.7% of background paths. Five checks with separate thresholds called 53.8%. One threshold for the full path maximum called 33.2%. Relative to separate thresholds, this rule reduced background calls by 20.6 percentage points and response calls by 3.2 points. It called 93.3% of response paths, including 84.4% by 100 ms. A rank proof gives a 25% marginal background bound for one future path under exchangeability. The data do not establish that assumption or demonstrate the bound. With three calibration paths, this deterministic rank rule cannot give a finite threshold at a 5% target. All eight processed source files passed full hash checks. All 1,042 saved pulse pairs matched a fresh extraction. The package contains input data, fitted readers, all scores and calls, three figures, the proof, and reproduction code. This is an offline measurement test in a reused clinical cohort. It does not measure continuous false commands or prove a neural origin for each response.

stereo-electroencephalography · SEEG · brain-computer interfaces · evoked responses · thresholds · rank calibration · background calls · signal processing · reproducibility

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References

4
  1. usesEight donor shapes gave less forecast error and 0.002 lower mean response AUC than eight cosines after five fit pulses at 86 SEEG sites in eight sessions sci:sha256:2a6f7f03fdc0a3d478dcf18e72daf6d41c9857ca607df84cba991a3aaed7402c

    This study uses its exact voltage arrays, event mappings, fixed contact choices, and extraction recipe. It tests new prefix thresholds on later pulses.

  2. usesFive calibration pulses gave mean later signed template AUC of 0.939 compared with 0.859 for one pulse in eight SEEG sessions sci:sha256:1d2aa103275ad7400befec4c899740ede8f2eb59a09897bdc3f4d4e190e54418

    This study keeps its first-five-pulse contact selection. The saved selection choices and candidate metadata define the 86 readouts used here.

  3. usesdoi:10.18112/openneuro.ds004696.v1.0.1

    The study uses processed voltage derivatives and event metadata from OpenNeuro ds004696 version 1.0.1; its files and exact hashes are recorded in the archived provenance.

  4. doi:10.1523/JNEUROSCI.2201-22.2023

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