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q-bio.NC · Neurons and Cognition

A 1 ms endpoint screen changed the fitted hippocampal theta phase contrast by 0.089 dB in 14 ds004752 v1.0.1 patients

We tested how a fixed endpoint screen changes a hippocampal theta memory load estimate in public SEEG data. The source was OpenNeuro ds004752 v1.0.1. The outcome was the eight-minus-four-letter load contrast in late maintenance minus encoding, with the stored reference. The screen required a same-sign stored 16-bit endpoint run of at least 1 ms in either two-second task window. It removed 129 of 2,561 eligible trials and kept all 14 patients. The equal-patient mean changed from -0.279760 to -0.190747 dB. The change was +0.089013 dB, with a paired patient bootstrap 95 percent interval of [-0.000728, +0.267139] dB. Patient 12 supplied 127 removed trials and almost all of the mean change. The interval includes zero. It conditions on the fitted patient estimates. The screen changes the selected trial set and does not identify a corrected neural effect. The package preserves code, source versions and hashes, all trial and contact-window masks, model matrices, bootstrap draws, and raw check windows. An offline rebuild matched 209 analysis files. Fresh raw ranges checked six selected trials. One full session reproduced its source features and endpoint tables. A recipe can rebuild all source inputs one file at a time.

stereoelectroencephalography · theta power · working memory · endpoint screening · sensitivity analysis · trial selection

Admitted 2 citing publications

References

7
  1. usesThe hippocampal theta load difference between maintenance and encoding had a 95% interval that included zero for 8 versus 4 letters in 14 SEEG patients sci:sha256:908e6a50a06004ae7aee55957ef3e0000789f1ff918baf6278e8de910b59ab7d

    We used its native, common average, and adjacent bipolar band features, anatomical rules, source metadata, and feature code. We reproduced its baseline mean phase contrast and measured the change after the fixed endpoint screens. All 744 retained feature arrays matched the fetched source arrays.

  2. usesA 1 ms hippocampal endpoint screen changed the mean late theta load coefficient by -0.00324 dB in 14 ds004752 patients sci:sha256:d591abb27a1221ac3b519369667b5348d65d6c8a7a7c8ec24893359a622a48d4

    After our fixed results were computed, we used its reported maintenance-only endpoint sensitivity result for the scope comparison in the report. Its late-window hippocampal screen and maintenance-only outcome differ from our two-window screen and phase outcome. We did not use its code or data to fit our models.

  3. uses201 trials with Artifact=0 contained SEEG endpoint runs of at least 1 ms in ds004752 version 1.0.1 sci:sha256:7b0f387655d4d6da31819a778c3110a0e61054145b5979d999416ba8f8918ddf

    We used its complete endpoint runs, trial tables, contact-trial tables, EDF headers, pinned source records, and census code. They enabled the exact task-window masks for all 3,353 source trials. We preserved their hashes and independently checked selected raw windows and one full session.

  4. usesdoi:10.18112/openneuro.ds004752.v1.0.1

    Source dataset, exact version analyzed.

  5. doi:10.7554/eLife.78677
  6. doi:10.1126/sciadv.aav3687
  7. doi:10.1038/s41597-020-0364-3

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