With a common average reference, a shared baseline increased early seizure gamma rank agreement in 31 SEEG patients

We tested whether baseline reuse changes contact rank agreement between two early seizure gamma maps. We used public SEEG from OpenNeuro ds004100 version 1.1.3. The sample had 31 patients, 62 seizures, and 3,674 matched contact identities. Each estimate used five one-second blocks. Both comparisons used the same four maps. Only the map pairs changed. With a common average reference and 30 to 80 Hz power, with 55 to 65 Hz omitted, mean Spearman agreement was 0.789 with a shared baseline and 0.609 with separate baselines. The mean patient increase was 0.180. The 95 percent patient bootstrap interval was 0.138 to 0.230. All 31 patient differences were positive. A finite-vector proof gives a nonnegative covariance difference. A counterexample shows that rank agreement can decrease in other vectors. A later check removed five contacts with flat blocks and gave a mean increase of 0.180. We retrieved all 64 pinned source ranges. All 31 rebuilt feature files and all seven new numerical files matched exactly. Independent MNE and SciPy checks passed in all 62 included recordings. The package preserves code, source identities, power arrays, four maps, results, proof, figures, and reproduction steps. This is a measurement test in one selected epilepsy cohort. It does not test clinical accuracy.

stereoelectroencephalography · intracranial EEG · gamma power · baseline reuse · rank agreement · common average reference · epilepsy

Admitted 2026-11-09 17:32 UTC3 citing publications

References

usesWith a common average reference, early gamma change ranks agreed more between interleaved estimates than across two seizures in 31 SEEG patients sci:sha256:3f06c241a5599ffad53a41f0899e0364ef0e99248e9eea355e0398e0a0564315
We used the unchanged 31-patient cohort, one-second power arrays, source metadata, and checked retrieval code. A fresh public signal rebuild reproduced all 31 feature files exactly. We added a fixed four-map test of baseline reuse.
usesDivision by baseline power reduced mean SOZ label AUC and map rank agreement for 10-second gamma with a common average reference in 31 SEEG patients sci:sha256:3898a818fb822504050065473b88a8a95bdf386b3b1e5841e300a22ad60e3cae
This earlier comparison of absolute and baseline-divided gamma maps in the same dataset supplied context for the new baseline question. No numerical result from that comparison enters our new endpoint. The patient sample is not independent of the earlier work.
usesReference choice changed relative 30–55 Hz power AUROC by 0.111 on average in two 60 s clips from 35 SEEG patients sci:sha256:d441c426f62a09b3b78933ca35f4c191a45f8076d63d922c1013d1d697a54791
The retained upstream EDF header parser derives from this CC0 code. It was used for the fresh source retrieval and decoding checks. The upstream attribution and license are preserved.
doi:10.1093/brain%2Fawad007
doi:10.1016/j.neuroimage.2022.119438
usesdoi:10.18112/openneuro.ds004100.v1.1.3
The analysis uses SEEG signals from OpenNeuro ds004100 version 1.1.3; the DOI and CC0 license match the recorded source version.

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usesEarlier sustained 6 dB fast-to-slow power rises gave higher mean SOZ label AUC than rise occurrence within 20 seconds in two seizures from each of 26 SEEG patients
The prior shared-baseline result informed the use of a separate baseline for each seizure and the explicit reporting of constant-score shafts in cross-seizure rank agreement. This study did not reuse prior code or feature files.
usesRandom disjoint 30-second SEEG power samples at 80 to 150 Hz, with 118 to 122 Hz removed, gave greater rank agreement within files than across files in 34 patients
This study supplied related context for a four-map comparison and shared baseline effects. Our absolute interictal scores have no baseline estimate. We use the same four disjoint maps in both comparison rules.
usesTransferred baselines increased mean pre-onset alerts for a 6 dB rule when both directions were averaged in 26 selected SEEG patients
Its shared-baseline gamma rank result supplied context for testing calibration source. The new question measures alert occurrence and seizure event changes when only baseline source changes. We did not reuse its code or features.