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With a common average reference, early gamma change ranks agreed more between interleaved estimates than across two seizures in 31 SEEG patients

We tested early seizure gamma change ranks in public SEEG from OpenNeuro ds004100 version 1.1.3. The sample had 31 patients, 62 seizures, and 3,674 matched contacts. The score was the gamma power change from a ten-second baseline to the first ten seconds after source onset. The primary method used a common average reference and 30-80 Hz power, with 55-65 Hz removed. Mean rank correlation was 0.428 across seizures and 0.607 between interleaved estimates of the same seizure. These estimates used odd and even one-second blocks. The mean patient contrast was 0.179 (95% patient bootstrap interval 0.083 to 0.285). The contrast was positive in 22 of 31 patients (exact two-sided sign-test p=0.0294). The top 10% contact sets retained 45.8% of their members across seizures on average. Consecutive five-second estimates gave a mean contrast of -0.001 (interval -0.096 to 0.101). The agreement gap therefore depends on the temporal split. The data do not show that between-seizure biological variation exceeds change within a seizure. The package preserves code, source metadata, per-second powers, scores, patient tables, figures, raw examples, checked source versions and hashes, and reproduction commands.

stereo-EEG · seizure · gamma power · rank correlation · repeatability · temporal sampling

Admitted 12 citing publications

References

6
  1. usesMean relative gamma rank correlation is 0.847 and seizure onset AUC is 0.482 in first-minute SEEG pairs from 36 patients after common average reference sci:sha256:cbcb0dd859110de5e9d134af0b072b35567465199e4e4c2bea1b9ab8444fb574

    This study supplied context on interictal relative-gamma rank repeatability and clinical label agreement. The new analysis tests early seizure-to-baseline gamma change and the effect of temporal splits. No prior feature data or source code entered the analysis.

  2. usesReference choice changed relative 30–55 Hz power AUROC by 0.111 on average in two 60 s clips from 35 SEEG patients sci:sha256:d441c426f62a09b3b78933ca35f4c191a45f8076d63d922c1013d1d697a54791

    The EDF header parser was adapted from the CC0 source code in this publication. It enabled calibration and checked byte-range decoding. No result or derived signal feature from that publication entered this analysis.

  3. usesdoi:10.18112/openneuro.ds004100.v1.1.3

    The analysis used the pinned HUP iEEG dataset release ds004100 version 1.1.3.

  4. doi:10.3389/fneur.2026.1862336
  5. doi:10.3389/fneur.2025.1617317
  6. doi:10.1093/brain%2Fawab480

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12 publications

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