With a common average reference, early gamma change gave lower mean SOZ label AUC than pre-onset power within contact name groups in two seizures from each of 30 SEEG patients
We compared fixed gamma scores with source seizure onset zone (SOZ) labels in public OpenNeuro ds004100 version 1.1.3 SEEG data. The primary test used two seizures from each of 30 patients, a common average reference, and SOZ/non-SOZ contact pairs in the same name group. Gamma power used 30-80 Hz with 55-65 Hz removed. Baseline was 20 to 10 seconds before onset. The seizure window was the first 10 seconds after onset. Mean AUC was 0.807 for pre-onset power and 0.649 for gamma change. The equal-patient difference was -0.158, with a patient bootstrap 95 percent interval of [-0.254, -0.066]. The interval assumes independent, exchangeable patients. Change gave lower AUC in 23 patients. The same mean direction appeared in the stored reference and planned nearby-contact checks. These results concern fixed score ranking. They do not measure added predictive information or clinical benefit. Fresh signal retrieval reproduced all 31 source feature files exactly. Independent signal checks passed for 62 records. The package preserves code, source versions and hashes, patient and pair tables, sampling draws, a retrieval recipe, and 13 exactly reproduced numerical output files.
stereoelectroencephalography · seizure onset zone · gamma power · intracranial EEG · baseline power · signal processing · AUC · epilepsy
References
4- usesWith a common average reference, early gamma change ranks agreed more between interleaved estimates than across two seizures in 31 SEEG patients sci:sha256:3f06c241a5599ffad53a41f0899e0364ef0e99248e9eea355e0398e0a0564315
We used all 31 saved signal feature files, source metadata, pinned retrieval records, and EDF feature code. Fresh retrieval reproduced all 31 feature files byte for byte. An added all-contact check repeated the source mean change AUC of 0.678246. The new primary test compares gamma change with pre-onset power within contact name groups.
- usesMean clinical seizure onset discrimination by local reference 70–150 Hz power was higher within shafts than across shafts in 20-second samples from eight selected SEEG cases sci:sha256:b4b255a5e0a63c3da0239270858bdec1697ea63b8c1735d6c8929633ddb33868
We read this report during the final context review after our primary analysis. Its within-shaft and across-shaft label comparisons supplied related spatial evidence for interpretation. Its interictal windows, local reference, high gamma score, and contact weights differ from our early seizure comparison. We did not use its data or code.
- usesdoi:10.18112/openneuro.ds004100.v1.1.3
Source dataset, HUP iEEG Epilepsy Dataset, version 1.1.3.
- doi:10.3389/fneur.2026.1862336
Cited by
3 publicationsPublic catalog entries on Sciscape.
- usesWith a common average reference, adding early gamma change gave mean onset label AUC 0.843 versus 0.803 within name groups in 14 test SEEG patients
We used its previous comparison to define the added-information question. We preserved its checked source feature arrays, metadata, signal extraction code, and retrieval recipes. We fit new models with separate training and test patients; we did not reuse its AUC estimates as new results.
- usesEarlier sustained 6 dB fast-to-slow power rises gave higher mean SOZ label AUC than rise occurrence within 20 seconds in two seizures from each of 26 SEEG patients
The prior comparison of gamma change with pre-onset power informed the fixed relative-power question and the focus on what event timing adds to occurrence. This study retrieved source signals anew and did not reuse prior code or feature files.
- usesThe post-to-pre gamma power ratio was lower at SOZ pairs than at unmarked pairs 10 to 30 seconds after marked seizure end in 31 SEEG patients
This work supplied prior context for comparison within contact name groups. The present test uses new post-offset signal ranges and local bipolar pairs. It uses no prior signal feature table.