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Mean delta-to-alpha change contrast was 0.069 dB 10 to 30 seconds after marked seizure end in 31 selected SEEG patients

We tested whether the delta-to-alpha power ratio rose more at seizure onset pairs than at unmarked pairs in the same contact name groups. We used 62 public recordings from 31 selected SEEG patients in OpenNeuro ds004100, version 1.1.3. We compared 10 to 30 seconds after marked seizure end with 60 to 40 seconds before marked seizure start. The mean marked minus unmarked change was 0.069 dB. The 95 percent patient bootstrap interval was -1.316 to 1.430 dB. The exact two-sided sign-flip p value was 0.923492. This test assumes independent patients and null sign symmetry. The ratio rose by 7.432 dB at marked pairs and 7.363 dB at unmarked pairs. At marked pairs, mean delta power fell by 3.339 dB and alpha power fell by 10.771 dB. A ratio increase therefore did not require an increase in absolute delta power. The primary result does not prove equal changes between the classes. The cohort and periods came from an earlier gamma study. This is an informed analysis of the same signals. The package contains new float64 features, code, raw check samples, source versions and hashes, figures, and repeat instructions.

intracranial EEG · seizure onset zone · delta power · alpha power · delta-to-alpha ratio · postictal activity

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References

4
  1. usesWith a common average reference, early gamma change ranks agreed more between interleaved estimates than across two seizures in 31 SEEG patients sci:sha256:3f06c241a5599ffad53a41f0899e0364ef0e99248e9eea355e0398e0a0564315

    This publication supplied upstream checked range retrieval and EDF parsing conventions. We received them through the cohort publication and preserved the attribution.

  2. usesThe post-to-pre gamma power ratio was lower at SOZ pairs than at unmarked pairs 10 to 30 seconds after marked seizure end in 31 SEEG patients sci:sha256:9a967db62b15eab677a62fca44947890d182bc07f061218855e485f2af4f7eb8

    This publication supplied the fixed 31-patient cohort, pair selection, source metadata, exact signal ranges and hashes, spectral conventions, and validation samples. We retrieved the same signal ranges again and computed new float64 delta and alpha features. Its gamma result informed the new question.

  3. usesReference choice changed relative 30–55 Hz power AUROC by 0.111 on average in two 60 s clips from 35 SEEG patients sci:sha256:d441c426f62a09b3b78933ca35f4c191a45f8076d63d922c1013d1d697a54791

    This publication supplied the original CC0 EDF header parser. We received the code through the two later publications and used it for pinned range retrieval.

  4. usesdoi:10.18112/openneuro.ds004100.v1.1.3

    The analyzed recordings came from OpenNeuro ds004100 version 1.1.3; its saved dataset metadata records this DOI and CC0 license.

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