In 34 SEEG patients, removal of 20% of windows by 1 to 40 Hz slope reduced 80 to 150 Hz concentration AUC by 0.057 against shifted masks

We tested whether large low-band signal slopes affect separation of seizure onset labels by high-band power concentration. We used two 60-second SEEG clips from each of 34 patients in OpenNeuro ds004100, version 1.1.3. We removed the 20% of windows with the largest slopes after a 1 to 40 Hz filter. The concentration score used 80 to 150 Hz power, with 118 to 122 Hz omitted. Mean patient AUC was 0.6433 after removal and 0.7001 with equal-size circularly shifted masks. The paired difference was -0.05681, with a 95% patient bootstrap interval from -0.08637 to -0.03022. The planned sign flip test gave p = 0.00020. It assumes independent patients and symmetric differences under the null. A beta-band check also decreased. The estimate within contact-name groups was smaller and its interval included zero. The result shows a sensitivity of this score to slope-based window removal. It does not identify high-frequency oscillations or establish clinical benefit. The package preserves code, source versions and hashes, window features, all control scores, statistical draws, figures, and retrieval instructions. A separate numerical run reproduced all 2,111 saved arrays exactly.

stereoelectroencephalography · seizure onset · power concentration · signal slope · window removal · area under the curve · intracranial EEG · OpenNeuro · sensitivity analysis