Mean MNI HFO spatial scores were above exchange and cyclic cluster reference means in the first hour of 18 SEEG sleep records

We tested first-hour spatial HFO counts in 18 public SEEG sleep records from OpenNeuro ds005398 version 1.1.3. HFO means high-frequency oscillation. The primary reference uniformly exchanged complete channel patterns between clusters with the same mark count. It kept minute totals and channel totals fixed. The mean normalized score was 1.8501. The patient bootstrap 95 percent interval was 1.4962 to 2.3111. An exploratory test kept cyclic order within size groups and used independent uniform shifts. Its mean score was 1.1480, with a bootstrap interval of 1.0781 to 1.2261. Both intervals assume independent, exchangeable patient sampling. Neither test had an exceedance in 9,999 conditional draws. Each added-one probability was 0.0001. Serial order raised the reference expectation in every patient. Excess remained under the cyclic model, which does not keep gaps or phase relations between size groups. These results apply to released MNI detector marks and the stated conditional assumptions. They do not prove biological rate changes or clinical benefit. The package preserves source versions, source bytes, code, exact count maps, draws, checks, and reproduction commands. All 90 result files matched a fresh-input repeat byte for byte.

high-frequency oscillations · stereoelectroencephalography · spatial counts · conditional randomization · epilepsy · OpenNeuro ds005398