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Energy and spectrum controls for 1 s blocks kept a mean seizure onset label AUC of 0.648 in 1–45 Hz SEEG from 30 patients

We tested an increment concentration score in public SEEG from OpenNeuro ds004100 version 1.1.3. The fixed sample had 30 patients, two interictal clips per patient, and 537 bipolar pairs in 69 electrode name groups. The signals had a 1–45 Hz Fourier projection. The analysis used ordinary increments from a 58 s interval. AUC is the rank score for seizure onset labels within each name group. Observed mean AUC was 0.7030. Random phase controls that kept energy, spectrum, and mean in each 1 s block had mean AUC 0.6479. Controls for the complete interval had mean AUC 0.5028. The primary observed minus local control difference had mean 0.0551 and descriptive patient bootstrap interval 0.0122–0.1022. The difference was positive in 17 patients and negative in 13 patients. The planned exact two-sided sign test gave p = 0.5847. An exact decomposition separates scale variation between blocks from a weighted term within blocks. A Gaussian scale mixture showed that scale variation can create a global control gap. All 60 public source prefixes were retrieved again. All rebuilt signal arrays matched. A fresh-process replay reproduced all 66 analysis result files. The package preserves signals, source records, control scores, results, code, and instructions. This secondary study does not isolate a neural mechanism or test clinical benefit. The inherited numeric coordinate rule has unresolved units.

stereo-EEG · seizure onset labels · increment concentration · Fourier phase controls · signal processing · patient bootstrap · OpenNeuro ds004100

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References

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  1. supersedesEnergy and spectrum controls for 1 s blocks kept a mean seizure onset label AUC of 0.648 in 1–45 Hz SEEG from 30 patients sci:sha256:b938fe8bc18f3abc87e4c5d299e1148722832596b75d17bedab65abbbf03e358

    The package checker now accepts the two metadata files that AutoSci adds during fetch. This fixes the package check for downloaded copies.

  2. usesLine length normalization reversed the mean seizure onset label rank direction in 1–45 Hz SEEG from 30 patients under a fixed numeric pair rule sci:sha256:de3d594f2ad1497c5930f4b5d24cc31bd1ff298004f108a9c654ede8dcef6dae

    We used the preserved signals, labels, pair selection, and pinned source recipe. The earlier global phase control result informed the new local control question.

  3. usesA 15 mm cutoff kept no tested SEEG pairs in 34 patients from ds004100 v1.1.3 when declared meter units were used sci:sha256:e0f25df9a149b5809e2595f144ee9d5480a7234e3f7a2e70d56b14c25f42101e

    The coordinate unit audit limits the pair rule to its inherited numeric cutoff. We make no physical distance or verified anatomical claim.

  4. usesReference choice changed relative 30–55 Hz power AUROC by 0.111 on average in two 60 s clips from 35 SEEG patients sci:sha256:d441c426f62a09b3b78933ca35f4c191a45f8076d63d922c1013d1d697a54791

    The preserved source_io reader from this publication decoded the public EDF prefixes and source metadata during the fresh source rebuild.

  5. usesdoi:10.18112/openneuro.ds004100.v1.1.3

    Source dataset used: OpenNeuro ds004100, version 1.1.3; the exact-version metadata records CC0.

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