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Line length normalization reversed the mean seizure onset label rank direction in 1–45 Hz SEEG from 30 patients under a fixed numeric pair rule

We tested line length in two 60 second interictal SEEG clips per patient. We used 1–45 Hz bipolar signals from 30 patients in OpenNeuro ds004100 version 1.1.3. Pairs followed an inherited numeric rule with unresolved coordinate units. Mean AUC within electrode name groups was 0.765 for line length and 0.324 after division by increment RMS. The fixed concentration score, one minus this ratio, gave AUC 0.676. Its descriptive 95 percent interval was 0.575 to 0.767. Controls with the same spectrum and new phases gave 0.505. All seven fixed checks kept the mean concentration AUC above 0.5. The score had less rank agreement between runs than raw line length. The package preserves 60 processed clips, a raw example, source pins, code, results, figures, and repeat commands. The sample is exploratory. It does not establish clinical accuracy, neural cause, or added value to a spectrum model.

stereoelectroencephalography · SEEG · line length · signal concentration · seizure onset · phase surrogates · area under the curve

Admitted 4 citing publications

References

6
  1. usesTime concentration of 80–150 Hz SEEG power gave a mean within-shaft AUC of 0.720 for seizure-onset pairs in 30 patients with two 60 s clips each sci:sha256:7ef8ec6049a5486c854f10f036b25fc59368c98c7d1a4b982aaad8209bef019f

    We reused the pinned source manifest, metadata, S3 recipes, cohort, QC records, and retrieval code. We retrieved all 60 selected signal prefixes again and rebuilt the QC. New outcomes measure 1–45 Hz voltage changes, not the earlier 80–150 Hz power endpoint.

  2. usesA 15 mm cutoff kept no tested SEEG pairs in 34 patients from ds004100 v1.1.3 when declared meter units were used sci:sha256:e0f25df9a149b5809e2595f144ee9d5480a7234e3f7a2e70d56b14c25f42101e

    The coordinate audit supplied evidence about the inherited numeric pair rule and declared meter units. We verified the source metadata again, retained the numeric rule for cohort continuity, and made no verified physical distance claim.

  3. usesReference choice changed relative 30–55 Hz power AUROC by 0.111 on average in two 60 s clips from 35 SEEG patients sci:sha256:d441c426f62a09b3b78933ca35f4c191a45f8076d63d922c1013d1d697a54791

    The unchanged source_io.py EDF reader and pair selection code came through the later concentration study package. We used them to calibrate public voltages and reconstruct the fixed contact and pair selection.

  4. usesdoi:10.18112/openneuro.ds004100.v1.1.3

    Source data and clinical labels: OpenNeuro ds004100 version 1.1.3, the exact release analyzed.

  5. doi:10.1109/IEMBS.2001.1020545
  6. doi:10.1016/S0167-2789(00)00043-9

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