Third moment asymmetry at 31.25 ms gave mean label concordance of 0.576 within name groups in paired interictal 1 to 45 Hz SEEG from 30 selected patients

We tested third moment temporal asymmetry in public SEEG from 30 selected patients. Each patient had two 60 second interictal clips in the 1 to 45 Hz band. The fixed lag was 31.25 ms. Mean clinical seizure onset label concordance within electrode name groups was 0.575649. Mean concordance for 39 fixed spectrum phase controls per pair and run was 0.502935. The mean patient difference was 0.072713, with a descriptive 95% bootstrap interval of -0.004170 to 0.144547. The difference was positive in 21 patients and negative in nine patients. The exact direction P value was 0.042774 under independent patients and equal sign probabilities. This test does not test a population mean. Mean pair rank correlation between runs was 0.359526. Concentration and raw line length gave higher mean correlations of 0.526863 and 0.936217. Clipping large increments reduced mean concordance to 0.535867. These results do not establish a stable clinical marker. All arrays in 60 signal inputs matched a rebuild from pinned public EDF prefixes. All 221 metadata files matched a fresh pinned Git checkout. The package preserves inputs, source code, controls, results, provenance, and reproduction instructions. Unresolved source coordinate units prevent physical pair distance claims.

SEEG · epilepsy · temporal asymmetry · third moment · interictal · phase controls · reproducibility