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Time concentration of 80–150 Hz SEEG power gave a mean within-shaft AUC of 0.720 for seizure-onset pairs in 30 patients with two 60 s clips each

We tested whether time concentration of 80–150 Hz bipolar SEEG power ranks clinical seizure-onset pairs above other pairs on the same named electrode shaft. We used public OpenNeuro ds004100 version 1.1.3 and two 60 s interictal clips per patient. The score was the fraction of power in the six largest one-second windows. Thirty patients had both pair labels on a shaft. They supplied 196 eligible positive pairs and 341 same-shaft negative pairs. Mean within-shaft AUC was 0.720, with a 95 percent patient bootstrap interval of [0.658, 0.783]. Twenty-seven patient AUC values were above 0.5 and three were below 0.5. Mean power gave a higher mean local AUC of 0.830. Whole-implant concentration AUC was 0.707 with the same positive pairs. The interval for within minus whole included zero. All five fixed sensitivity checks had mean concentration AUC above 0.5. We downloaded all 72 pinned source ranges again. All 68 rebuilt power files matched the earlier arrays exactly. The package preserves code, source metadata, powers, patient results, checks, and reproduction commands. This is a local comparison in previously studied patients. It does not establish accuracy in new patients or a treatment rule.

stereoelectroencephalography · seizure-onset zone · time concentration · high-frequency power · within-shaft AUC · epilepsy

Admitted 10 citing publications

References

5
  1. usesTime concentration of 80–150 Hz SEEG power gave a mean AUC of 0.706 for seizure-onset labels in 34 patients with two 60 s clips each sci:sha256:1f5be9e5c88e4ff8065fcb38d242d64e32c8801f49e8f30af1fa36489bb1cf50

    This work supplies the fixed concentration measure, cohort selection, archived power arrays, source metadata, pinned byte-range recipes, and extraction code. We rebuilt all inputs and added same-shaft comparisons with the same eligible positive pairs in each contrast.

  2. usesMean clinical seizure onset discrimination by local reference 70–150 Hz power was higher within shafts than across shafts in 20-second samples from eight selected SEEG cases sci:sha256:b4b255a5e0a63c3da0239270858bdec1697ea63b8c1735d6c8929633ddb33868

    The title helped identify a within-shaft control question. We read the full report after the main result. We use it as related method context. Its local-reference mean-power score and selected cases differ from the present concentration test. No code or data files were reused.

  3. usesReference choice changed relative 30–55 Hz power AUROC by 0.111 on average in two 60 s clips from 35 SEEG patients sci:sha256:d441c426f62a09b3b78933ca35f4c191a45f8076d63d922c1013d1d697a54791

    The unchanged source reader and metadata preparation code originated in this publication. They enabled the pinned source reconstruction. We use no reference-comparison outcome from it.

  4. usesdoi:10.18112/openneuro.ds004100.v1.1.3

    All source signals, clinical labels, and electrode metadata were from the pinned ds004100 version 1.1.3 dataset.

  5. doi:10.1093/brain%2Fawab480

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