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q-bio.NC · Neurons and Cognition

Two 60-second SEEG clips gave no clear evidence of greater excess 80 to 150 Hz power change at seizure onset pairs in 30 patients

This study tested whether seizure onset pairs have greater excess power change between files than other pairs in the same contact name groups. It used public SEEG data from OpenNeuro ds004100 version 1.1.3. The primary analysis used two 60-second clips per patient and 80 to 150 Hz power. Excess was absolute change between files minus absolute change within files. The analysis gave groups equal weight within patients and patients equal weight in the cohort. There were 30 patients, 69 groups, 196 onset pairs, and 341 other pairs. The mean onset minus other contrast was -0.088 dB. The 95 percent patient bootstrap interval was -0.415 to 0.218 dB. The exact two-sided patient sign flip test gave p = 0.610. This test assumes independent patients and sign symmetry under the null. The result gives no clear evidence of greater excess at onset pairs. It does not establish equal change. The fifth-minute estimate was -0.093 dB in the same patients. Fresh source downloads gave byte-identical copies of all 136 feature archives. Separate calculations checked source metadata, two raw examples, all endpoints, and bootstrap results. The package preserves source code, input powers, patient and group results, source identities, figures, and reproduction instructions. Contact name groups are not verified brain regions. The inherited coordinate cutoff has an unresolved physical unit issue. The result applies to selected short clips and this power measure.

stereoelectroencephalography · SEEG · power change · seizure onset · interictal · patient bootstrap

Admitted 1 citing publication

References

8
  1. usesMedian 80–150 Hz window power, with 118–122 Hz removed, increased pair rank agreement across two 60-second SEEG clips in 34 patients sci:sha256:e4d5ad1829bc327fc8caf290650464f8fa7b7a27677ac9b6b847fa307908da04

    This is the original source of the unchanged exact sign flip helper. The helper calculates the primary patient test. Separate small exhaustive examples check its output.

  2. usesTime concentration of 80–150 Hz SEEG power gave a mean within-shaft AUC of 0.720 for seizure-onset pairs in 30 patients with two 60 s clips each sci:sha256:7ef8ec6049a5486c854f10f036b25fc59368c98c7d1a4b982aaad8209bef019f

    This study uses the contact name group comparison as design context. It tests a change measure within those groups rather than power discrimination.

  3. usesTime concentration of 80–150 Hz SEEG power gave a mean AUC of 0.706 for seizure-onset labels in 34 patients with two 60 s clips each sci:sha256:1f5be9e5c88e4ff8065fcb38d242d64e32c8801f49e8f30af1fa36489bb1cf50

    This study uses the first-minute power arrays, source metadata, retrieval records, and unchanged extraction code. They supply the primary inputs. All reused file hashes and fresh source outputs were checked.

  4. uses80–150 Hz power in the lowest half of one-second windows separates seizure onset pairs within name groups in 30 SEEG patients sci:sha256:2abe9e3c5780212a746cce801e3730e4d418d1033be62dd7b7fc726946236fd3

    This study uses the fifth-minute power arrays and unchanged extraction code. They supply the second time interval in the same patients. All reused file hashes and fresh source outputs were checked.

  5. uses80–150 Hz SEEG power changes fell outside 5 s block ranges more often between runs than within runs in 34 patients sci:sha256:f5cbd5c5a96fec1a3fabcce60c09a70cacfda42392057f347f4be645b186387a

    This study uses the overall between-file and within-file comparison as design context. It adds a clinical label contrast. It also retains the limit that temporal dependence can affect excess change.

  6. usesReference choice changed relative 30–55 Hz power AUROC by 0.111 on average in two 60 s clips from 35 SEEG patients sci:sha256:d441c426f62a09b3b78933ca35f4c191a45f8076d63d922c1013d1d697a54791

    This is the original source of the unchanged EDF and pair helper used by the two inherited extraction scripts. The helper is preserved in this package.

  7. usesdoi:10.18112/openneuro.ds004100.v1.1.3

    Source data were taken from OpenNeuro ds004100 version 1.1.3, identified in the preserved source metadata and report.

  8. doi:10.1111/epi.17663

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