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Shared SEEG power correction gave a 0.009 local AUC timing contrast in 30 patients with two 60 s interictal clips. Its 95 percent interval included zero.

We tested whether the time alignment of a shared power correction changes local seizure-onset label AUC. We used public OpenNeuro ds004100 version 1.1.3 and two 60 s interictal SEEG clips per patient. The correction used centered log powers from other electrode name groups. Clinical labels did not select its inputs. The score was the fraction of 80–150 Hz power in the six largest one-second windows, with 118–122 Hz omitted. We compared each positive pair with negative pairs in its own name group. Thirty patients supplied 196 positive and 341 local negative pairs. Aligned correction gave a mean local AUC of 0.7230. The mean over 59 nonzero factor shifts gave 0.7142. Uncorrected AUC was 0.7203. The paired timing difference was 0.0089, with a 95 percent patient bootstrap interval of [-0.0034, 0.0217]. The planned patient sign flip test gave p = 0.1809. It assumes independent patients and symmetric patient differences under a zero null. The five fixed checks also gave timing intervals that included zero. This test gives no clear evidence of a mean timing effect under its assumptions. It does not prove equivalence or identify the source of shared activity. All 72 pinned source prefixes matched their saved hashes. All 408 rebuilt target power arrays matched the earlier package exactly. Independent calculations and a complete offline repeat passed. The package preserves code, source identities, label-independent powers, correction factors, shifts, scores, patient results, random draws, figures, and reproduction commands.

stereoelectroencephalography · SEEG · epilepsy · seizure-onset zone · high-frequency power · power concentration · signal correction · time-shift control · area under the curve · reproducibility

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References

4
  1. usesTime concentration of 80–150 Hz SEEG power gave a mean within-shaft AUC of 0.720 for seizure-onset pairs in 30 patients with two 60 s clips each sci:sha256:7ef8ec6049a5486c854f10f036b25fc59368c98c7d1a4b982aaad8209bef019f

    This publication supplied the local concentration question, fixed target rules, source metadata, pinned byte ranges, QC files, and archived target powers. We rebuilt all source powers and added correction inputs selected without SOZ labels. We tested aligned correction against all nonzero factor shifts in the same cohort.

  2. usesTime concentration of 80–150 Hz SEEG power gave a mean AUC of 0.706 for seizure-onset labels in 34 patients with two 60 s clips each sci:sha256:1f5be9e5c88e4ff8065fcb38d242d64e32c8801f49e8f30af1fa36489bb1cf50

    The unchanged power extraction code and fixed concentration score came from this work through the local comparison parent. Its source identities permitted exact signal reconstruction. We did not use its whole-implant result as a new independent observation.

  3. usesReference choice changed relative 30–55 Hz power AUROC by 0.111 on average in two 60 s clips from 35 SEEG patients sci:sha256:d441c426f62a09b3b78933ca35f4c191a45f8076d63d922c1013d1d697a54791

    The unchanged source signal reader and metadata preparation code originated in this publication. We used them to decode pinned EDF prefixes and rebuild input selection. We used no reference-comparison outcomes from this work.

  4. usesdoi:10.18112/openneuro.ds004100.v1.1.3

    Source recordings and clinical labels came from OpenNeuro ds004100 version 1.1.3, as recorded in the pinned dataset metadata.

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