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The six largest beta and high-band power windows overlapped more at seizure-onset pairs than at other pairs in the same contact name group in two 60-second clips per patient in 30 SEEG patients

This study tested whether large powers in two bands occurred in the same windows more often at seizure-onset pairs. It used public SEEG from OpenNeuro ds004100 version 1.1.3. Each of 30 patients supplied two 60-second interictal clips. The method selected the six largest one-second powers in each band. Beta was 13 through 30 Hz. The high band was 80 through 150 Hz, with 118 through 122 Hz excluded. The comparison used 196 seizure-onset pairs and 341 other pairs in 69 contact name groups. Each patient had equal weight. The mean overlap was 25.04 percent at seizure-onset pairs and 16.26 percent at other pairs. The difference was 8.78 percentage points. Its 95 percent patient bootstrap interval was 4.77 to 12.95 points. The two-sided patient sign-flip p value was 0.000235. This test assumes independent patients and symmetric differences under the null hypothesis. Five fixed sensitivity checks gave the same direction. Pair ranks had low agreement between clips. All 68 input files were rebuilt from pinned public source ranges. All 748 arrays matched exactly. Separate score and signal checks passed. The package preserves code, data, source records, random assignments, and reproduction instructions. The result is a label association in brief clips. It does not establish a neural cause or clinical benefit. Contact name groups are an unverified proxy for electrode shafts.

stereo-EEG · seizure onset · beta power · high-band power · window overlap · interictal recordings · electrophysiology

Admitted 4 citing publications

References

4
  1. usesTime concentration of 80–150 Hz SEEG power gave a mean within-shaft AUC of 0.720 for seizure-onset pairs in 30 patients with two 60 s clips each sci:sha256:7ef8ec6049a5486c854f10f036b25fc59368c98c7d1a4b982aaad8209bef019f

    This publication informed the contact name group comparison and the weighting of each positive pair within a patient. The new study uses those design choices to test the shared timing of beta and high-band extreme power windows.

  2. usesTime concentration of 80–150 Hz SEEG power gave a mean AUC of 0.706 for seizure-onset labels in 34 patients with two 60 s clips each sci:sha256:1f5be9e5c88e4ff8065fcb38d242d64e32c8801f49e8f30af1fa36489bb1cf50

    This publication supplied the 68 window-power input files, source records, metadata, raw example, quality records, and extractor. A fresh retrieval rebuilt every feature array. The new analysis measures shared window timing rather than power concentration.

  3. usesReference choice changed relative 30–55 Hz power AUROC by 0.111 on average in two 60 s clips from 35 SEEG patients sci:sha256:d441c426f62a09b3b78933ca35f4c191a45f8076d63d922c1013d1d697a54791

    This publication supplied the original EDF decoder and source preparation code. Both source files are preserved unchanged and used in the source reconstruction.

  4. usesdoi:10.18112/openneuro.ds004100.v1.1.3

    The analyzed source is the HUP iEEG Epilepsy Dataset, OpenNeuro ds004100 version 1.1.3; the publication records its pinned source identities and hashes.

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